PLoS Computational Biology

Neuroscience

Alcoholism may be caused by dynamical dopamine imbalance

An international research collaborative has identified potential alcoholism mechanisms associated with altered dopaminergic neuron response to complex dynamics of prefrontal cortex neurones affecting dopamine release.

Neuroscience

Breaking memory circuits with marijuana

Paranoia. Munchies. Giggles. Sleepiness. Memory loss. Although the effects of cannabinoids–the active components of marijuana–are familiar to many, their neurobiological substrates are poorly characterized. Perhaps the ...

Health

Sunrise and sunset guide daily activities of city-dwellers

Despite artificial lightning and social conventions, the dynamics of daylight still influence the daily activities of people living in modern, urban environments, according to new research published in PLOS Computational ...

Neuroscience

Complex environments push 'brain' evolution

Little animations trying to master a computer game are teaching neuroscience researchers how the brain evolves when faced with difficult tasks.

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