PLoS Computational Biology

Neuroscience

New theory of synapse formation in the brain

The human brain keeps changing throughout a person's lifetime. New connections are continually created while synapses that are no longer in use degenerate. To date, little is known about the mechanisms behind these processes. ...

Neuroscience

No cable spaghetti in the brain

Our brain is a mysterious machine. Billions of nerve cells are connected such that they store information as efficiently as books are stored in a well-organized library. To this date, many details remain unclear, for instance ...

Medical research

New insights into the complexity of the brain

A recent study out of the Complexity Science Hub (CSH) Vienna paves the way to a deeper insight into the complexity of the human brain, one of the largest and most sophisticated organs in the human body. The study—which ...

Oncology & Cancer

Predicting metastasis from primary tumor size

A new mathematical model uses the size of a cancer patient's initial, primary tumor to predict whether undetectable secondary tumors are already present. Stefano Avanzini and Tibor Antal of the University of Edinburgh, U.K., ...

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