PLoS Genetics

Diabetes' genetic underpinnings can vary based on ethnic background, studies say

Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine.

Diabetes created 3 hours ago | popularity not rated yet | comments 0 | with audio podcast

Recently published research targets malaria mosquito control woes

(Medical Xpress)—Malaria is responsible for about 700,000 deaths annually in sub-Saharan Africa alone, and a team of Texas A&M University researchers is doing their best to help stem this perpetual tide of human suffering.

Genetics created May 07, 2013 | popularity not rated yet | comments 0 | with audio podcast

A history lesson from genes: Using DNA to tell us how populations change

When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as ...

Genetics created Jan 09, 2013 | popularity 4 / 5 (6) | comments 1 | with audio podcast

Major genetic discovery explains 10 percent of aortic valve disease

Researchers at the Sainte-Justine University Hospital Center and University of Montreal have identified genetic origins in 10% of an important form of congenital heart diseases by studying the genetic variability within families.

Genetics created Sep 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

Diabetic fruit flies support buzz about dietary sugar dangers

Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at San ...

Genetics created Jan 17, 2013 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Scientists find new gene markers for cancer risk

A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...

Genetics created Mar 27, 2013 | popularity 5 / 5 (4) | comments 1

Measuring enzyme levels in cancer patients may reveal healthy cells' ability to survive chemotherapy

New research from MIT may allow scientists to develop a test that can predict the severity of side effects of some common chemotherapy agents in individual patients, allowing doctors to tailor treatments ...

Genetics created Apr 05, 2013 | popularity not rated yet | comments 0 | with audio podcast

Starr collaboration illuminates mysterious pathway to immortality in cancer cells

(Medical Xpress) -- Cancer cells are immortal because they circumvent failsafe mechanisms that stop out-of-control cell proliferation. One of these mechanisms – the progressive shortening of chromosomes ...

Cancer created Jul 25, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Cell contents may be key to controlling toxicity of Huntington's disease protein

New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.

Genetics created Jun 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Gene discovery points towards non-hormonal male contraceptive

A new type of male contraceptive could be created thanks to the discovery of a key gene essential for sperm development.

Genetics created May 24, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Researchers identify genetic markers for testosterone, estrogen level regulation

A research study led by Boston University School of Medicine (BUSM) and the University of Exeter in the United Kingdom, in collaboration with a global consortium, has identified genetic markers that influence a protein involved ...

Genetics created Jul 20, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Genetic differences may influence sensitivity to pain, study finds

The study, published in PLOS Genetics on 20 December, adds to growing evidence that particular genes are involved in chronic pain and highlights this pathway as a potential target for more effective pain relief treatments for pa ...

Genetics created Dec 20, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

With two new methods, scientists hope to improve genome-wide association studies

As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...

Genetics created Apr 26, 2013 | popularity not rated yet | comments 0 | with audio podcast

Five genes have been found to determine human facial shapes

Five genes have been found to determine human facial shapes, as reported by researchers from the Netherlands, Germany, Canada, the United Kingdom, and Australia in the open-access journal PLOS Genetics.

Genetics created Sep 13, 2012 | popularity 4 / 5 (5) | comments 0 | with audio podcast

New research a step closer to male contraceptive pill

(Medical Xpress)—New insights into sperms' swimming skills shed light on male infertility, which affects one in 20 men, and could provide a new avenue to the development of a male contraceptive pill.

Genetics created Oct 08, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast