PLoS Genetics

Genetics

New drugs more likely to be approved if backed up by genetics

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts. Emily King and colleagues ...

Health

Heavy smoking causes faces to look older

"Smoker's Face," a condition where smokers look older than they are, is just one of many negative effects caused by heavy tobacco usage. Louise Millard of the University of Bristol and colleagues report these findings in ...

Oncology & Cancer

CRISPR-edited C. elegans identifies vulnerabilities in cancer

A one-millimeter worm, the nematode Caenorhabditis elegans, is an animal model widely used in biomedical research by hundreds of laboratories around the world. Surprisingly, it has approximately the same number of genes that ...

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