PLoS Genetics
Measuring enzyme levels in cancer patients may reveal healthy cells' ability to survive chemotherapy
New research from MIT may allow scientists to develop a test that can predict the severity of side effects of some common chemotherapy agents in individual patients, allowing doctors to tailor treatments ...
Genetics
Apr 05, 2013 |
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Scientists find new gene markers for cancer risk
A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian ...
Genetics
Mar 27, 2013 |
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Cell contents may be key to controlling toxicity of Huntington's disease protein
New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.
Genetics
Jun 06, 2012 |
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Recently published research targets malaria mosquito control woes
(Medical Xpress)—Malaria is responsible for about 700,000 deaths annually in sub-Saharan Africa alone, and a team of Texas A&M University researchers is doing their best to help stem this perpetual tide of human suffering.
Genetics
May 07, 2013 |
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With two new methods, scientists hope to improve genome-wide association studies
As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...
Genetics
Apr 26, 2013 |
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Pathway controlling cell growth revealed
A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.
Cancer
Feb 18, 2013 |
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Researchers create new air sacs in mouse model of emphysema using novel growth factor
In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead ...
Medical research
Feb 14, 2013 |
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Colon cancer exhibits a corresponding epigenetic pattern in mice and humans
Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...
Genetics
Feb 07, 2013 |
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Diabetic fruit flies support buzz about dietary sugar dangers
Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at San ...
Genetics
Jan 17, 2013 |
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Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...
Genetics
Jan 10, 2013 |
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A history lesson from genes: Using DNA to tell us how populations change
When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as ...
Genetics
Jan 09, 2013 |
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Genetic differences may influence sensitivity to pain, study finds
The study, published in PLOS Genetics on 20 December, adds to growing evidence that particular genes are involved in chronic pain and highlights this pathway as a potential target for more effective pain relief treatments for pa ...
Genetics
Dec 20, 2012 |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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A class of RNA molecules protects germ cells from damage, researchers show
Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.
Genetics
Nov 15, 2012 |
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New research a step closer to male contraceptive pill
(Medical Xpress)—New insights into sperms' swimming skills shed light on male infertility, which affects one in 20 men, and could provide a new avenue to the development of a male contraceptive pill.
Genetics
Oct 08, 2012 |
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