PLoS Pathogens

New discovery may lead the way to improved whooping cough vaccine

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine. The findings could help reduce the incidence ...

Diseases, Conditions, Syndromes created May 13, 2013 | popularity not rated yet | comments 0

Scientists confirm Justinianic Plague caused by bacterium Yersinia pestis

(Medical Xpress)—From the several pandemics generally called 'pestilences' three are historically recognized as due to plague, but only for the third pandemic of the 19th-21st centuries AD there were microbiological ...

Diseases, Conditions, Syndromes created May 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Scientists reveal how deadly Marburg virus silences immune system

Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Marburg virus, a close cousin of Ebola virus. These viruses cause similar diseases and are some of ...

Medical research created Sep 13, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Mutant parasite could stop malaria in its tracks

(Medical Xpress)—University of Nottingham Malaria experts have found a way of disabling one of the many phosphatase proteins which breathe life into the malaria parasite. The result is a mutant which is ...

Diseases, Conditions, Syndromes created Sep 21, 2012 | popularity 4.5 / 5 (4) | comments 0 | with audio podcast

'Bas-Congo': Genetic sleuthing uncovers deadly new virus in Africa

An isolated outbreak of a deadly disease known as acute hemorrhagic fever, which killed two people and left one gravely ill in the Democratic Republic of Congo in the summer of 2009, was probably caused by ...

Diseases, Conditions, Syndromes created Sep 27, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Drug-resistant MRSA bacteria: Here to stay in both hospital, community

(Medical Xpress)—The drug-resistant bacteria known as MRSA, once confined to hospitals but now widespread in communities, will likely continue to exist in both settings as separate strains, according to ...

Diseases, Conditions, Syndromes created Mar 15, 2013 | popularity 4.8 / 5 (5) | comments 7 | with audio podcast

Deadly virus discovered in bats also jumps species

(Medical Xpress)—Four new forms of hantavirus, one of the most virulent pathogens transmitted from animals to humans, have been identified by international research contributed to by the University of Sydney.

Diseases, Conditions, Syndromes created Feb 08, 2013 | popularity 4.7 / 5 (6) | comments 0 | with audio podcast

'Defective' virus surprisingly plays major role in spread of disease

(Medical Xpress)—Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new ...

Diseases, Conditions, Syndromes created Feb 28, 2013 | popularity 5 / 5 (6) | comments 0 | with audio podcast

New foot-and-mouth vaccine signals huge advance in global disease control

(Medical Xpress)—A new vaccine against foot-and-mouth disease that is safer to produce and easier to store has been developed by scientists from the University of Oxford and The Pirbright Institute.

Diseases, Conditions, Syndromes created Mar 28, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Two-pronged immune cell approach could lead to universal shot against flu

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific ...

Medical research created Mar 14, 2013 | popularity 4.5 / 5 (2) | comments 1 | with audio podcast

Influenza virus: Being the most beneficial mutation is no guarantee of long-term genetic success, research finds

(Medical Xpress)—Wellcome Trust Sanger Institute scientists have used computer modelling to understand why some mutations in a virus gene rise to dominance and become 'fixed' in the genome of the virus, ...

Diseases, Conditions, Syndromes created Jan 03, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Breast milk kills HIV and blocks its oral transmission in humanized mouse

More than 15 percent of new HIV infections occur in children. Without treatment, only 65 percent of HIV-infected children will live until their first birthday, and fewer than half will make it to the age of ...

HIV & AIDS created Jun 14, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

To spread, nervous system viruses sabotage cell, hijack transportation

Herpes and other viruses that attack the nervous system may thrive by disrupting cell function in order to hijack a neuron's internal transportation network and spread to other cells.

Medical research created May 30, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Malaria parasite protein identified as potential new target for drug treatment

Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments ...

Medical research created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Statin drug shows promise for fighting malaria effects

Researchers have discovered that adding lovastatin, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of ...

Diseases, Conditions, Syndromes created Dec 27, 2012 | popularity not rated yet | comments 0 | with audio podcast