Proceedings of the National Academy of Sciences

Competing antibodies may have limited the protection achieved in HIV vaccine trial in Thailand

Continuing analysis of an HIV vaccine trial undertaken in Thailand is yielding additional information about how immune responses were triggered and why the vaccine did not protect more people.

HIV & AIDS created May 06, 2013 | popularity not rated yet | comments 0 | with audio podcast

Boosting 'cellular garbage disposal' can delay the aging process, research shows

(Medical Xpress)—UCLA life scientists have identified a gene previously implicated in Parkinson's disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, ...

Genetics created May 06, 2013 | popularity 4.8 / 5 (18) | comments 1 | with audio podcast

Heroin vaccine blocks relapse in preclinical study

Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing ...

Medical research created May 06, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Effects of stress on brain cells offer clues to new anti-depressant drugs

Research from King's College London reveals the detailed mechanism behind how stress hormones reduce the number of new brain cells - a process considered to be linked to depression. The researchers identified a key protein ...

Neuroscience created May 06, 2013 | popularity 3.9 / 5 (7) | comments 0 | with audio podcast

Breast milk ingredient could prevent necrotizing enterocolitis—deadly intestinal problem in preemies

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of ...

Diseases, Conditions, Syndromes created May 06, 2013 | popularity not rated yet | comments 2 | with audio podcast

Scientists create personalized bone substitutes from skin cells

A team of New York Stem Cell Foundation (NYSCF) Research Institute scientists report today the generation of patient-specific bone substitutes from skin cells for repair of large bone defects. The study, led by Darja Marolt, ...

Medical research created May 06, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers discover endogenous antibiotic in the brain

Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. ...

Medical research created May 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

PTSD research: Distinct gene activity patterns from childhood abuse

Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, ...

Psychology & Psychiatry created May 01, 2013 | popularity 4 / 5 (4) | comments 0 | with audio podcast

'Traffic' in our cells works both for and against us

A mechanism that permits essential substances to enter our cells while at the same time removing from them harmful components also has a "down side." This negative aspect prevents vital drugs, such as anti-cancer drugs, from ...

Medical research created May 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists find mutation driving pediatric brain tumors

A type of low-grade but sometimes lethal brain tumor in children has been found in many cases to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors, report scientists at ...

Genetics created Apr 30, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Size, wiring of brain structures in kids predict benefit from math tutoring, study says

(Medical Xpress)—Why do some children learn math more easily than others? Research from the Stanford University School of Medicine has yielded an unexpected new answer.

Neuroscience created Apr 29, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Study identifies key shift in the brain that creates drive to overeat

A team of American and Italian neuroscientists has identified a cellular change in the brain that accompanies obesity. The findings could explain the body's tendency to maintain undesirable weight levels, rather than an ideal ...

Medical research created Apr 29, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Neuroscientists use statistical model to draft fantasy teams of neurons

This past weekend teams from the National Football League used statistics like height, weight and speed to draft the best college players, and in a few weeks, armchair enthusiasts will use similar measures ...

Neuroscience created Apr 29, 2013 | popularity 4 / 5 (5) | comments 0 | with audio podcast

Big data analysis identifies prognostic RNA markers in a common form of breast cancer

A Big Data analysis that integrates three large sets of genomic data available through The Cancer Genome Atlas has identified 37 RNA molecules that might predict survival in patients with the most common form of breast cancer.

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Disrupting cell signals may lead to new cancer treatments

(Medical Xpress)—Scientists have taken a major step towards developing new treatments for certain cancers by disrupting the internal cellular signals that lead to the uncontrolled growth of cancerous cells.

Cancer created Apr 29, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast