Proceedings of the National Academy of Sciences

Parkinson's & Movement disorders

Novel test holds promise for detecting Parkinson's disease early

In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms. But without a test that can detect these changes, it's difficult ...

Diseases, Conditions, Syndromes

Using machine learning to track the evolution of COVID-19

Scientists have developed a machine-learning approach to track the evolution of SARS‑CoV‑2, the virus that causes COVID-19, and potentially other viruses, according to a study published in the Proceedings of the National ...

Medications

A new drug candidate can shrink kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...

Oncology & Cancer

Protein 'brake' could help develop new cancer treatments

Some cancerous tumors hijack proteins that act as "brakes" on our immune system and use them to form a sort of shield against immune recognition. Immunotherapy treatments have been created that turn off these "brakes" and ...

Oncology & Cancer

Scientists show reprogrammed fat cells support tumor growth

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the German Cancer Research Center (DKFZ) ...

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