Science Translational Medicine

Researchers reverse bone loss in immune disorder

Patients with leukocyte adhesion deficiency, or LAD, suffer from frequent bacterial infections, including the severe gum disease known as periodontitis. These patients often lose their teeth early in life.

Mar 26, 2014
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Beta-catenin alters T cells in lasting and harmful ways

Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the February 26, 2014, issue ...

Feb 26, 2014
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