Science Translational Medicine

A surprise mechanism uncovered in the development of lupus

In a study with a surprising outcome, scientists at Yale School of Medicine have discovered that an enzyme complex known for promoting natural resistance to bacteria and fungi unexpectedly inhibits the development ...

Diseases, Conditions, Syndromes created Oct 25, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Combining imaging and gene analysis could transform breast cancer diagnosis

Combining two approaches - one that digitally scans images of tumour samples and another that analyses genetic information - gives a more accurate prediction of how breast cancer will behave. The research ...

Cancer created Oct 25, 2012 | popularity not rated yet | comments 0

New drug to target and destroy tumor cells developed

A new drug created at the University of Minnesota may hold the answer to defeating pancreatic cancer, according to results published today in the prestigious journal Science Translational Medicine.

Cancer created Oct 18, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Epigenetic analysis of stomach cancer finds new disease subtypes

Researchers at the Duke-NUS Graduate Medical School in Singapore have identified numerous new subtypes of gastric cancer that are triggered by environmental factors.

Cancer created Oct 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Comparing family history and genetic tests for predicting complex disease risk

In a new theoretical study, 23andMe, the personal genetics company, developed a mathematical model which shows that family history and genetic tests offer different strengths. The study results suggest that both family history ...

Genetics created Oct 15, 2012 | popularity not rated yet | comments 0

Workshop calls for more detailed reporting in animal studies

A workshop sponsored by NIH's National Institute of Neurological Disorders and Stroke (NINDS) has produced a set of consensus recommendations to improve the design and reporting of animal studies. By making animal studies ...

Other created Oct 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Human neural stem cells study offers new hope for children with fatal brain diseases

Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital have demonstrated for the first time that banked human neural stem cells—HuCNS-SCs, a proprietary product of StemCells ...

Medical research created Oct 10, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study shows evidence that transplanted neural stem cells produced myelin

A Phase I clinical trial led by investigators from the University of California, San Francisco and sponsored by Stem Cells Inc., showed that neural stem cells successfully engrafted into the brains of patients and appear ...

Medical research created Oct 10, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

World's first successful clinical trial to protect the brain from damage caused by stroke

A team of Canadian scientists and clinicians, led by Dr. Michael Hill of the Calgary Stroke Program at Foothills Medical Centre and University of Calgary's Hotchkiss Brain Institute (HBI), have demonstrated that a neuroprotectant ...

Neuroscience created Oct 09, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

50-hour whole genome sequencing provides rapid diagnosis for children with genetic disorders

Today investigators at Children's Mercy Hospitals and Clinics in Kansas City reported the first use of whole genome information for diagnosing critically ill infants. As reported in Science Translational Medicine, the te ...

Genetics created Oct 03, 2012 | popularity 5 / 5 (5) | comments 4 | with audio podcast

New mouse model of debilitating lung disease suggests potential treatment regimen

LAM, short for pulmonary lymphangioleiomyomatosis, affects about 1 in 10,000 women of childbearing age and is characterized by proliferation of smooth muscle-like cells in the lung, destruction of lung tissue, and growth ...

Medical research created Oct 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Healthy lungs' microbes focus of study on cystic fibrosis

(Medical Xpress)—Healthy people's lungs are home to a diverse community of microbes that differs markedly from the bacteria found in the lungs of cystic fibrosis patients. That's the result of new research from Stanford ...

Medical research created Sep 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers define two categories of multiple sclerosis patients

There are approximately 400,000 people in the United States with multiple sclerosis. Worldwide, the number jumps to more than 2.1 million people. Rather than a one-size-fits-all approach to treating the millions with multiple ...

Neuroscience created Sep 26, 2012 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Fragile X study offers new drug hope

(Medical Xpress)—An experimental drug can improve sociability in patients with fragile X syndrome and may be helpful as a treatment for autism, according to a study.

Autism spectrum disorders created Sep 24, 2012 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Video games help patients and health care providers

(Medical Xpress)—Can video games help patients with cancer, diabetes, asthma, depression, autism and Parkinson's disease? A new publication by researchers from the University of Utah, appearing in the Sept ...

Medical research created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast