Science Translational Medicine

Researchers implicate unique cell type in multiple sclerosis

Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation ...

Diseases, Conditions, Syndromes created Aug 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

Substance involved in Alzheimer's can reverse paralysis in mice with multiple sclerosis

A molecule widely assailed as the chief culprit in Alzheimer's disease unexpectedly reverses paralysis and inflammation in several distinct animal models of a different disorder — multiple sclerosis, Stanford University ...

Medical research created Aug 01, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Rapamycin effective in mouse model of inherited heart disease and muscular dystrophies

Rapamycin, an immunosuppressant drug used in a variety of disease indications and under study in aging research labs around the world, improved function and extended survival in mice suffering from a genetic mutation which ...

Medical research created Jul 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

Heart medication converts cancer cells into vaccine

(HealthDay) -- A class of heart medications, cardiac glycosides, can induce immunogenic cell death (ICD), whereby dying cancer cells are converted into a vaccine that stimulates antitumor response, according ...

Cancer created Jul 23, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Certain heart meds may give chemo a boost

(HealthDay) -- When common heart drugs such as digitalis and digoxin are combined with some chemotherapy drugs, the effect appears to be an increase in the death of cancer cells, according to French researchers.

Cancer created Jul 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Animal model replicates human immune response against HIV, could revolutionize HIV vaccine research

One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue ...

HIV & AIDS created Jul 18, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Personalized medicine closer to reality: Study uses stem cells to study variants of Parkinson’s disease

A nationwide consortium of scientists at 20 institutions, led by a principal faculty member at the Harvard Stem Cell Institute (HSCI), has used stem cells to take a major step toward developing personalized ...

Medical research created Jul 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study finds switch that lets early lung cancer grow unchecked

Cellular change thought to happen only in late-stage cancers to help tumors spread also occurs in early-stage lung cancer as a way to bypass growth controls, say researchers at Mayo Clinic in Florida. The finding, reported ...

Cancer created Jul 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Two proteins offer a 'clearer' way to treat Huntington's disease

In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critic ...

Neuroscience created Jul 11, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

'Molecular grenade': Drug from Mediterranean weed kills tumor cells in mice

Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel -- undetected by normal cells -- through the bloodstream until activated by ...

Cancer created Jul 09, 2012 | popularity 5 / 5 (18) | comments 2 | with audio podcast

New detector for rare cancer cells

(Medical Xpress) -- Researchers in the US have developed a new detector for measuring rare circulating tumor cells (CTCs) in samples of whole blood.

Cancer created Jul 07, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast report

Patient-derived stem cells could improve drug research for Parkinson's

Researchers have taken a step toward personalized medicine for Parkinson's disease, by investigating signs of the disease in patient-derived cells and testing how the cells respond to drug treatments. The study was funded ...

Parkinson's & Movement disorders created Jul 04, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers develop novel anti-body vaccine that blocks addictive nicotine chemicals from reaching the brain

Researchers at Weill Cornell Medical College have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction.

Medical research created Jun 27, 2012 | popularity 5 / 5 (7) | comments 7 | with audio podcast

Successful transplant of patient-derived stem cells into mice with muscular dystrophy

Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Tr ...

Medical research created Jun 27, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Injecting life-saving oxygen into a vein: Microparticles could deliver oxygen when breathing is impaired

Patients unable to breathe because of acute lung failure or an obstructed airway need another way to get oxygen to their blood—and fast—to avoid cardiac arrest and brain injury. A team led by researchers at Boston ...

Medical research created Jun 27, 2012 | popularity 4.9 / 5 (11) | comments 3 | with audio podcast