Science Translational Medicine

NOX4 implicated in fibrosis

Genkyotex, a developer of selective NOX enzyme inhibitors, announced today the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse lung fibrosis associated with aging in ...

Apr 11, 2014
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Microparticles fight inflammation post-heart attack

After a heart attack, much of the damage to the heart muscle is caused by inflammatory cells that rush to the scene of the oxygen-starved tissue. But that inflammatory damage is slashed in half when microparticles ...

Jan 15, 2014
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Researchers reverse bone loss in immune disorder

Patients with leukocyte adhesion deficiency, or LAD, suffer from frequent bacterial infections, including the severe gum disease known as periodontitis. These patients often lose their teeth early in life.

Mar 26, 2014
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