Stem Cell Reports

Medical research

Stem cells may help replace lost sensory neurons

Sensory neurons of the peripheral nervous system, which sense touch, temperature, and pain, can be permanently lost during infections and trauma, in response to certain medications, and in diabetic patients with peripheral ...

Medical research

Researchers develop novel platform to improve immunotherapy

Recent advances in immunotherapy for cancer have stimulated a plethora of studies aimed at developing T cells (white blood cells) and Natural Killer (NK) cells (immune cells with enzymes that can kill tumor cells or cells ...

Diseases, Conditions, Syndromes

Researchers home in on a new cause of Stargardt disease

Using a new stem-cell based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE). ...

Genetics

Researchers develop gene therapy for rare ciliopathy

Researchers from the National Eye Institute (NEI) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early ...

Cardiology

Study finds two protein pathways downregulated in postnatal heart

In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...

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