The human cardiac voltage-gated sodium channel (Nav1.5) plays a critical role in maintaining regular heartbeats. Mutations in Nav1.5 cause life-threatening heart rhythm disorders (arrhythmias).
Apr 9, 2018
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A study published in the scientific journal Structure (Cell Press) describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ...
Feb 27, 2018
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In most cases, prostate cancer is cured by surgery and/or radiotherapy. However, 20 percent of patients will need treatment to remove tumour cells but this treatment ceases to be effective after two or three years and the ...
Dec 13, 2017
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A discovery in a protein associated with glaucoma was so unheard of that for over two years, researchers ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially ...
Oct 20, 2017
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The near-spherical outer structure of the dengue virus has been recreated in remarkable detail by a team of bioinformaticians in Singapore. The virtual model could show researchers how the virus fuses with and infects human ...
Jan 25, 2017
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Enzymes called kinases manage a wide range of cell processes, from metabolism, cell signaling, nutrient transport, and many others. Because they can affect so many different cell activities, kinases are tightly regulated ...
Nov 9, 2016
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In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming ...
Sep 22, 2016
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New insights into the potential for new classes of HIF inhibitors to restore control of the hypoxia response—representing the potential foundation of a new cancer-fighting strategy—are the focus of recently published ...
Sep 13, 2016
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Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.
Aug 19, 2016
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In amyotrophic lateral sclerosis, aggregates of the protein TDP-43 are almost always found in afflicted neurons and glial cells. Meanwhile, about 50 ALS-linked mutations are known to affect a particular region of TDP-43. ...
Aug 18, 2016
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