Structure is a peer-reviewed scientific journal founded by Wayne A. Hendrickson, Carl-Ivar Brändén and Alan R. Fersht in September 1993. It focuses on protein structure and related issues. The journal is published monthly by Cell Press. The current editors are Christopher D. Lima and Andrej Sali.
In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming ...
Sep 22, 2016
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What causes neurons to die in Parkinson's disease? Parkinson's disease is a long-term (chronic) neurological condition that affects around 12,000 people in Ireland and between 7 and 10 million people worldwide.
Feb 13, 2020
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A discovery in a protein associated with glaucoma was so unheard of that for over two years, researchers ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially ...
Oct 20, 2017
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Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation—a discovery that could have important implications for the treatment of allergies, ...
Aug 27, 2015
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Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed the structure and function of a drug called LY3361237, which can reduce the harmful activity of the immune system ...
Jun 5, 2023
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Experiments led by researchers at the Department of Energy's Oak Ridge National Laboratory have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the ...
Nov 16, 2020
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Groundbreaking new findings by UC Irvine and German chemists about how cataracts form could be used to help prevent the world's leading cause of blindness, which currently affects nearly 20 million people worldwide.
Dec 5, 2013
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In amyotrophic lateral sclerosis, aggregates of the protein TDP-43 are almost always found in afflicted neurons and glial cells. Meanwhile, about 50 ALS-linked mutations are known to affect a particular region of TDP-43. ...
Aug 18, 2016
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It is difficult to underestimate the importance of telomerase, an enzyme that is the hallmark of both aging and the uncontrolled cell division associated with cancer. In an effort to understand and control telomerase activity, ...
Sep 19, 2013
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In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, ...
Jun 15, 2016
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