New treatments for depression are needed that act rapidly and also have sustained effects. Ketamine accomplishes this, but toxic side effects limit its long-term use. Scientists haven't understood how ketamine was able to ...
Feb 29, 2024
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Purdue University researchers have developed a patented therapeutic strategy for Lowe syndrome, an incurable and rare genetic disorder, by repurposing two drugs previously approved by the U.S. Food and Drug Administration ...
Feb 29, 2024
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Drug discovery can be a frustrating process of trial and error. Scientists using fragment-based drug discovery link fragments of different molecules together to create a more potent drug but may not know whether a compound ...
Feb 28, 2024
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Many cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved through expedited ("fast track") pathways, finds a study published by The BMJ.
Feb 28, 2024
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The therapeutic drug rapamycin, which is normally used in cancer therapy and after organ transplants, can extend the lifespan and health span of laboratory animals. Understanding how rapamycin extends lifespan is important, ...
Feb 28, 2024
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A study by the Institut de Neurociències of the UAB (INc-UAB) demonstrates in animal models the benefits of vorinostat after having suffered a stroke. The drug, used in humans to treat cutaneous T-cell lymphoma, has been ...
Feb 28, 2024
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A doctor at the Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, in Philadelphia, found that a patient at the center had experienced a false positive urine test after taking empagliflozin, an SGLT2 ...
The currently recommended five-day course of molnupiravir, an antiviral treatment, may not be long enough to treat COVID-19, according to a new paper involving UCL researchers.
Feb 27, 2024
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Heart disease researchers have identified a group of patients for whom international guidelines on aspirin use for heart health may not apply.
Feb 27, 2024
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Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers ...
Feb 27, 2024
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