EU approves Avastin for lung cancer

August 24, 2007

The European Union has approved the anti-cancer drug Avastin as a first-line treatment for advanced lung cancer.

European officials said the drug, which is already approved in the United States, can be used as a first-line treatment for patients with advanced non-small cell lung cancer in combination with platinum-based chemotherapy.

Swiss drug maker Roche said Avastin is the only first-line therapy to demonstrate improved survival benefits beyond one year in patients with advanced lung cancer, the company said Friday in a release.

Roche said Avastin is the first treatment that inhibits angiogenesis, which is the growth of a network of blood vessels that supply nutrients and oxygen to cancerous tissues.

Avastin targets a naturally occurring protein called VEGF (Vascular Endothelial Growth Factor), a key mediator of angiogenesis, thus choking off the blood supply that is essential for the growth of the tumor and its spread throughout the body

The drug is also used in the treatment of breast, colorectal and kidney cancers.

Copyright 2007 by United Press International

Explore further: FDA approves Roche's Avastin for ovarian cancer

Related Stories

Avastin no benefit to older lung cancer patients: study

April 17, 2012

(HealthDay) -- Medicare patients who have advanced non-small cell lung cancer appear to get no survival benefit from adding the drug Avastin to standard chemotherapy, researchers from the Dana-Farber Cancer Institute report.

US revokes Roche's Avastin for breast cancer

November 18, 2011

US health officials on Friday revoked the authorization of Roche's Avastin for breast cancer treatment, saying it concluded the drug had "not been shown to be safe and effective for that use."

Studies: Avastin may fight early breast cancers

January 25, 2012

Surprising results from two new studies may reopen debate about the value of Avastin for breast cancer. The drug helped make tumors disappear in certain women with early-stage disease, researchers found.

Avastin disappoints against ovarian cancer

December 28, 2011

Avastin, the blockbuster drug that just lost approval for treating breast cancer, now looks disappointing against ovarian cancer, too. Two studies found it did not improve survival for most of these patients and kept their ...

Recommended for you

Universal flu vaccine designed by scientists

September 30, 2016

An international team of scientists have designed a new generation of universal flu vaccines to protect against future global pandemics that could kill millions.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.