Anti-aging hormones: Little or no benefit and the risks are high

April 13, 2010

In the wake of the American Medical Association's (AMA) Council on Science and Public Health's recently released report "The use of hormones for "anti-aging": a review of efficacy and safety," a leading medical authority has criticized the use of anti-aging hormones.

Dr. Thomas T. Perls, an associate professor of medicine at Boston University School of Medicine has long spoken out against the promotion and distribution of growth hormones for non-medical uses such as anti-aging and sports.

In an editorial appearing in the Future Medicine journal Aging Health, Dr. Perls applauds the courage and example displayed by the AMA in its recently published assessment of the risks and benefits of growth hormone, , estrogen and DHEA for anti-aging. The editorial entitled "Anti-aging medicine: what should we tell our patients?" is freely available at

There have always been nostrums and potions peddled for eternal youth. Most recently these have been what some entrepreneurs call "bio-identical" or "all-natural" hormones. What they mean by these terms varies from substances made from vegetables - such as soy or yams, which some claim have estrogen-like effects to, more commonly, drugs that are exactly the same as hormones prescribed by endocrinologists for specific diseases. Dr. Perls remarked: "The terms bio-identical or all-natural, particularly in the case of the drugs prescribed by endocrinologists, misleadingly convey a sense of safety to the gullible customer. Arsenic is all-natural to, and it even has some medical uses, but it is anything but safe."

"The AMA's review of the risks and benefits of these hormones in the setting of anti-aging and athletic enhancement is very important given its inclusion of the consensus and position statements of the key professional medical societies as well as the federal agencies that guard public health." states Dr. Perls in the editorial.

The editorial summarizes the AMA's assessment for each of the purported anti-aging hormones and essentially the bottom line of his argument is that in terms of anti-aging, the risks of these hormones out-weigh the little or no benefit. Dr. Perls denounces the marketing of these hormones, particularly growth and anabolic steroids (anabolic steroids are variations of testosterone), for anti-aging. He also provides guidelines for spotting "red flags of quackery" and basic advice that physicians can lend to their patients in their pursuit of healthy aging.

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Apr 13, 2010
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not rated yet Apr 13, 2010
This is the problem the consumer has. Many of us beleive there is enough knowledge out there to help us all live longer/better already and that aging is a slow disease cause by loss of normal function in every thing, this may be treatable in some cases but which? How do we know whos telling the truth when some people want to sell us hormones and some want to sell us medicines, and doctors seem more and more corrupted by the industry.
not rated yet Apr 13, 2010
ssshhhh - slaveunit, that is the point! you let people who believe it'll work to test it. Than you trend and monitor them to see if they grow another head. If not, than all is well :) If they grow a stub, ah it's acceptable :P

Next we have spermidine and it's effects on increasing life span's in time magazine fyi. Watch out ladies we've got lifespan boosters in our testicles. (now let the imagination go and convince the ladies hahah)

It's like the hype with resveratrol(sp?) They tout that u can drink red wine. But little do people know, u can just eat grapes with skin. But hey, people wanna have that reason to binge drink on red wine :P

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