Potential diagnostic test for Alzheimer's would use cerebrospinal fluid

Researchers at the University of Kentucky are working on a potential diagnostic test for Alzheimer's disease, based on biomarkers in cerebrospinal fluid.

Scout Diagnostics, a company targeting early diagnosis of , recently received matching funds of $435,600 to support developing a laboratory test to detect and confirm Alzheimer's disease in its earliest stages. Scout was formed in 2006 by University of Kentucky chemistry professors and Sanders-Brown Center on Aging researchers Mark Lovell and Bert Lynn, along with CEO John Beran.

Lovell and Lynn have been working for some time with for Alzheimer's disease. They have identified specific markers for Alzheimer's in cerebrospinal fluid. The potential exists for researchers to develop a diagnostic test for early Alzheimer's using analysis of spinal fluid samples. This would be a significant development, as existing treatments for Alzheimer's disease are most effective if started extremely early in the progression of the disease — often before clinical signs of cognitive impairment are apparent.

The UK Sanders-Brown Center on Aging also maintains a large cohort of research volunteers, many of whom have donated cerebrospinal fluid for research on the .

"We were very pleased to hear of this award for the cutting-edge research that Dr. Lovell and his team at Scout Diagnostics are doing. A reliable biomarker for Alzheimer's disease is desperately needed to identify individuals very early in the disease process, so that therapeutic interventions can begin when they may be most effective, before memory problems develop," said Linda Van Eldik, director of the Sanders-Brown Center on Aging.

Provided by University of Kentucky

not rated yet
add to favorites email to friend print save as pdf

Related Stories

More accurate diagnosis of Alzheimer's

Apr 19, 2011

A new study from the University of Gothenburg, Sweden, shows how analysing spinal fluid can help to detect Alzheimer's disease at an early stage. The researchers behind the study hope that their findings will contribute to ...

Recommended for you

Global Ebola toll rises to 5,689: WHO

3 hours ago

The World Health Organization said Thursday that the global death toll from the Ebola virus had increased to 5,689 out of a total of 15,935 cases of infection, mainly in western Africa.

Ebola vaccine promising in first human trials

13 hours ago

Researchers say they're a step closer to developing an Ebola vaccine, with a Phase 1 trial showing promising results, but it will be months at the earliest before it can be used in the field.

At one month, US Ebola monitors finding no cases

16 hours ago

The U.S. program that requires weeks of monitoring for travelers from African countries with Ebola reaches the one-month mark Thursday. And so far, no cases of the disease have turned up.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.