Use of topical corticosteroids in children with eczema does not have negative side effects

April 21, 2011 in Medications

A new study published in the journal Pediatric Dermatology reveals that routine, long-term use of topical corticosteroids (TCS) for treating children with eczema does not cause any significant, negative side effects.

Parental phobia of TCS is widespread and leads to poorly managed in . The commonest fear is that TCS use will "thin the skin." Parents fears are also shared by many , including pharmacists.

Led by Gayle Fischer, MBBS, FACD, of The University of Sydney, researchers studied 92 children, 70 of which were part of the study/dermatitis group while the other 22 were categorized in a control group. Researchers convinced the parents of these 70 children to use enough TCS to control their children's eczema very well so that they were virtually free of eczema consistently. The 22 children in the control group were not using TCS.

Researchers then evaluated the children by examining them for any signs of skin thinning and by also examining their treated and untreated skin by dermoscopy, a technique which utilizes a mini-microscope to search for even the most subtle signs of TCS side effects.

They found that the children using TCS had no evidence of skin thinning even though they were using enough TCS to produce complete control of their eczema. These children were no different to the children who were not using TCS at all.

"Our results show that normal routine use of TCS does not cause skin thinning, and parents should be reassured. We hope that our work will give them the confidence to use TCS safely and effectively" Fischer notes.

Provided by Wiley search and more info website

2 /5 (1 vote)  

Rank 2 /5 (1 vote)
Relevant PhysicsForums posts

More news stories

Acne pill benefits outweigh blood clot risk: EU agency

Europe's medicines watchdog said Friday the benefits of acne drug Diane-35, also widely used as a contraceptive, outweigh the risk of developing blood clots in the veins—when correctly prescribed.

Medications created 19 hours ago | popularity not rated yet | comments 0

First influenza vaccine brought to clinical testing

Singapore's Agency for Science, Technology and Research (A*STAR) and Switzerland's Cytos Biotechnology AG today announced that the first healthy volunteer has been dosed in a Phase 1 clinical trial with their ...

Medications created 20 hours ago | popularity not rated yet | comments 0

Aspirin not always best treatment for many individuals

(Medical Xpress)—An aspirin a day may not always keep heart disease away, say two University of Florida cardiologists. But a new algorithm they have developed outlines factors physicians should weigh as ...

Medications created May 16, 2013 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

FDA: lower ambien's dose to prevent drowsy driving

(HealthDay)—The U.S. Food and Drug Administration has approved new, lower-dose labeling for the popular sleep drug Ambien (zolpidem) in an effort to cut down on daytime drowsiness that could be a hazard ...

Medications created May 15, 2013 | popularity not rated yet | comments 0

Simponi approved for ulcerative colitis

(HealthDay)—Simponi (golimumab) injection has been approved by the U.S. Food and Drug Administration to treat adults with moderate-to-severe ulcerative colitis.

Medications created May 15, 2013 | popularity not rated yet | comments 0


AIDS science at 30: 'Cure' now part of lexicon

Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.

For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests

Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...

Melon focus headband turns to Kickstarter for rollout plans

(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...

Temporal processing in the olfactory system

The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...

Now we know why old scizophrenia medicine works on antibiotics-resistant bacteria

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...

Individuals who drink heavily and smoke may show 'early aging' of the brain

Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic. Multiple factors can influence both the type and degree of neurocognitive abnormalities ...