Advanced-stage prostate cancer patients experience 20-year survival rates with surgery

May 15, 2011 in Cancer

Long-term survival rates for patients with advanced prostate cancer suggest they can be good candidates for surgery, Mayo Clinic researchers have found. Their study found a 20-year survival rate for 80 percent of patients diagnosed with cancer that has potentially spread beyond the prostate, known as cT3 prostate cancer, and treated with radical prostatectomy, or surgery to remove the prostate gland. Previously, patients found to have cT3 prostate cancer were offered radiation or hormone treatment, but not radical prostatectomy.

The researchers presented their findings during the American Urological Association Annual Meeting in Washington.

"We are doing a much better job of identifying and expanding candidates for surgery, which results in better, longer outcomes for so many of our patients," says R. Jeffrey Karnes, M.D., of Mayo Clinic's Department of Urology. "We have confirmed that patients diagnosed with locally advanced can enjoy a long, cancer-free interval."

The 80 percent survival rate for cT3 diagnoses at 20 years compares to 90 percent for cT2, or cancer confined to the prostate. This long-term follow-up of patients who underwent surgery between 1987 and 1997 is an important advance in understanding the quality outcomes for cT3 patients. The study sample included patients diagnosed and operated on between 1987 and 1997. Ongoing research will examine contemporary data.

Provided by Mayo Clinic search and more info website

not rated yet  

Rank not rated yet
Relevant PhysicsForums posts
  • Math and dyslexia?
    created16 hours ago
  • portable metabolism meter?
    createdMay 21, 2012
  • Rare medical conditions on 20/20 tonight
    createdMay 18, 2012
  • "Good" Cholesterol in Doubt
    createdMay 17, 2012
  • A couple of questions about schizophrenia
    createdMay 17, 2012
  • Paralyzed woman uses thoughts to move robotic arm
    createdMay 17, 2012
  • More from Physics Forums - Medical Sciences

More news stories

Scientists unravel role of fusion gene in prostate cancer

Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill ...

Cancer created 11 minutes ago | popularity not rated yet | comments 0 | with audio podcast

Early-life risk factors for non-Hodgkin lymphoma

Factors influencing early life non-Hodgkin lymphoma (NHL) incidence include family characteristics, high fetal growth, older maternal age, low birth order, and male gender, according to a study published May 22 in the Journal of ...

Cancer created 11 minutes ago | popularity not rated yet | comments 0

Do bald men face higher risk of prostate cancer?

(HealthDay) -- Got hair? If you don't, you might have a higher risk of prostate cancer, a preliminary study suggests.

Cancer created 2 hours ago | popularity not rated yet | comments 0 | with audio podcast

Researchers present new findings for novel pancreatic cancer vaccine

A novel pancreatic cancer vaccine shows promise in improving survival when added to standard treatment, according to new research out of University Hospitals Case Medical Center's Seidman Cancer Center and Case Western Reserve ...

Cancer created 3 hours ago | popularity not rated yet | comments 0

Researchers create new anti-cancer drug

A team of University of Hawaii Cancer Center scientists led by James Turkson, Ph.D. have created a new type of anti-cancer drug named BP-1-102. The drug, which can be orally administered, targets a key protein that triggers ...

Cancer created 6 hours ago | popularity 5 / 5 (1) | comments 0


Studies examine CPAP treatment and cardiovascular outcomes in adults with obstructive sleep apnea

Two studies that included adults with obstructive sleep apnea examined the effectiveness of reducing the risk of cardiovascular outcomes, including high blood pressure, by treatment with continuous positive airway pressure ...

Systems treating severe heart attacks expanding nationwide

The number of systems of care that quickly transfer and treat heart attack patients has increased substantially across the nation, according to research published in Circulation: Cardiovascular Quality and Outcomes, an American ...

Use of multicomponent intervention linked with decrease in using physical restraint in nursing homes

Nursing homes that used a multicomponent intervention that included staff training and supportive materials for staff, residents and relatives had a lower rate of use of physical restraints such as bilateral bed rails and ...

Limits to growth: Scientists identify key metastasis-enabling enzyme

(Medical Xpress) -- On the complex road to eradicating cancer, controlling or preventing metastatic growth initiated by primary tumors is high on the to-do list. A key area of such research is the development ...

Body building, diet supplements linked to liver damage: study

(HealthDay) -- Body-building and weight-loss products are the types of dietary supplements most likely to cause liver injury, according to a small new study.

Learning and memory: The role of neo-neurons revealed

(Medical Xpress) -- Researchers at the Institut Pasteur and the CNRS have recently identified in mice the role played by neo-neurons formed in the adult brain. By using selective stimulation the researchers ...