'Bad' cholesterol not as bad as people think, study shows

May 5, 2011 in Medical research

The so-called "bad cholesterol" – low-density lipoprotein commonly called LDL – may not be so bad after all, shows a Texas A&M University study that casts new light on the cholesterol debate, particularly among adults who exercise.

Steve Riechman, a researcher in the Department of Health and Kinesiology, says the study reveals that LDL is not the evil Darth Vader of health it has been made out to be in recent years and that new attitudes need to be adopted in regards to the substance. His work, with help from colleagues from the University of Pittsburgh, Kent State University, the Johns Hopkins Weight Management Center and the Northern Ontario School of Medicine, is published in the Journal of Gerontology.

Riechman and colleagues examined 52 adults from ages to 60 to 69 who were in generally good health but not physically active, and none of them were participating in a training program. The study showed that after fairly vigorous workouts, participants who had gained the most also had the highest levels of LDL (bad) , "a very unexpected result and one that surprised us.

"It shows that you do need a certain amount of LDL to gain more muscle mass. There's no doubt you need both – the LDL and the HDL -- and the truth is, it (cholesterol) is all good. You simply can't remove all the 'bad' cholesterol from your body without serious problems occurring.

Cholesterol is found in all humans and is a type of fat around the body. A person's total cholesterol level is comprised of LDL (low-density lipoprotein) and HDL (high-density lipoprotein) cholesterol.

LDL is almost always referred to as the "bad" cholesterol because it tends to build up in the walls of arteries, causing a slowing of the blood flow which often leads to heart disease and heart attacks.

HDL, usually called the "good cholesterol," often helps remove cholesterol from arteries.

"But here is where people tend to get things wrong," Riechman says.

"LDL serves a very useful purpose. It acts as a warning sign that something is wrong and it signals the body to these warning signs. It does its job the way it is supposed to.

"People often say, 'I want to get rid of all my bad (LDL) cholesterol,' but the fact is, if you did so, you would die," the Texas A&M professor adds. "Everyone needs a certain amount of both LDL and HDL in their bodies. We need to change this idea of LDL always being the evil thing – we all need it, and we need it to do its job."

According to the American Heart Association, about 36 million American adults have high cholesterol levels.

"Our tissues need cholesterol, and LDL delivers it," he notes. "HDL, the good cholesterol, cleans up after the repair is done. And the more LDL you have in your blood, the better you are able to build muscle during resistance training."

Riechman says the study could be helpful in looking at a condition called sarcopenia, which is muscle loss due to aging. Previous studies show muscle is usually lost at a rate of 5 percent per decade after the age of 40, a huge concern since muscle mass is the major determinant of physical strength. After the age of 60, the prevalence of moderate to severe sarcopenia is found in about 65 percent of all men and about 30 percent of all women, and it accounts for more than $18 billion of health care costs in the United States.

"The bottom line is that LDL – the – serves as a reminder that something is wrong and we need to find out what it is," Riechman says.

"It gives us warning signs. Is smoking the problem, is it diet, is it lack of exercise that a person's cholesterol is too high? It plays a very useful role, does the job it was intended to do, and we need to back off by always calling it 'bad' cholesterol because it is not totally bad."

Provided by Texas A&M University

not rated yet  

Rank not rated yet
Relevant PhysicsForums posts
  • Poor nutrition leading to overeating?
    created3 hours ago
  • Math and dyslexia?
    createdMay 21, 2012
  • portable metabolism meter?
    createdMay 21, 2012
  • Rare medical conditions on 20/20 tonight
    createdMay 18, 2012
  • "Good" Cholesterol in Doubt
    createdMay 17, 2012
  • A couple of questions about schizophrenia
    createdMay 17, 2012
  • More from Physics Forums - Medical Sciences

More news stories

Array of light for early disease detection?

A special feature in this week's issue of the journal Science highlights protein array technology, touching on research conducted by Joshua LaBaer, director of the Biodesign Institute's Virginia G. Piper ...

Medical research created 11 hours ago | popularity not rated yet | comments 0 | with audio podcast

Researchers spearhead groundbreaking research into treatment of brain swelling

Researchers at Trinity College Dublin have reported the results of groundbreaking research into the prevention of cerebral oedema or swelling of the brain, a major cause of death in people who have sustained a traumatic injury ...

Medical research created 15 hours ago | popularity not rated yet | comments 0 | with audio podcast

FDA clears test for mastocytosis diagnosis

The Food and Drug Administration has approved a new test to help physicians diagnose a group of rare cell disorders. The test, or assay, was developed by an expert at Virginia Commonwealth University in the field of mast ...

Medical research created 16 hours ago | popularity not rated yet | comments 0

Novel biomarkers reveal evidence of radiation exposure

Researchers at the Medical College of Wisconsin have identified novel biomarkers that could be used to confirm exposure to damaging radiation in large groups of people potentially exposed to unknown and variable doses for ...

Medical research created 16 hours ago | popularity not rated yet | comments 0

Stem cell research paves way for progress on dealing with Fragile X retardation

Researchers at the Hebrew University of Jerusalem have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. The discovery paves the way for research that will examine restoration ...

Medical research created 18 hours ago | popularity not rated yet | comments 0


Scientists turn patients' skin cells into heart muscle cells to repair their damaged hearts

For the first time scientists have succeeded in taking skin cells from heart failure patients and reprogramming them to transform into healthy, new heart muscle cells that are capable of integrating with existing heart tissue.

Scientists start explaining Fat Bastard's vicious cycle

Fat Bastard's revelation "I eat because I'm depressed and I'm depressed because I eat" in the Austin Powers film series may be explained by sophisticated neuroscience research being undertaken by scientists affiliated with ...

Socioeconomics may affect toddlers' exposure to flame retardants

A Duke University-led study of North Carolina toddlers suggests that exposure to potentially toxic flame-retardant chemicals may be higher in nonwhite toddlers than in white toddlers.

Pathological aging brains contain the same amyloid plaques as Alzheimer's disease

Pathological aging (PA) is used to describe the brains of people which have Alzheimer's disease (AD)-like pathology but where the person showed no signs of cognitive impairment whilst they were alive. New research, published ...

Breast MRI helps predict chemotherapy's effectiveness

Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online ...

Kids suffer long-term from parents' smoking: study

Children exposed to their parents' cigarette smoke are at greater risk of suffering serious cardiovascular health problems later in life, a study showed Wednesday.