Use of clot busters for stroke increased from 2005 to 2009, but still low
The use of clot-busting drugs to treat acute ischemic stroke increased from 2005 through 2009 but is still low, according to research reported in Stroke: Journal of the American Heart Association.
Clot-busting drugs are known as thrombolytics, and tissue plasminogen activator (tPA) is the only FDA-approved thrombolytic for treating acute ischemic stroke, which is caused by a blood clot in the brain.
Although the study didn't follow patients after hospital discharge, "we believe that the increased treatment rate has the potential to reduce the overall burden of stroke disability and morbidity," said Opeolu Adeoye, M.D., lead author of the study and assistant professor of emergency medicine and neurosurgery at the University of Cincinnati in Ohio.
Using Medicare records and pharmacy billing codes, researchers found 1.1 percent to 1.4 percent of acute ischemic stroke patients received a thrombolytic drug in 2005, and 3.4 percent to 3.7 percent did in 2009.
In a further calculation, the researchers assumed that some or all of the billings for unapproved thrombolytics and/or treating hemorrhagic stroke were billing errors, or represented an ischemic stroke that subsequently developed some bleeding, which occasionally occurs. This upped the use of tPA, Adeoye said, which led to a conservative estimate that 3.4 percent to 5.2 percent or 23,800 to 36,000 of the 700,000 Americans who had an ischemic stroke in 2009 received tPA.
Treatment with a clot-busting drug is most effective as soon as possible after stroke symptoms begin ideally within the first hour, according to American Heart Association/American Stroke Association guidelines. But, doctors can give tPA to some patients up to 4.5 hours after symptoms begin.
Provided by American Heart Association
- Drug may improve outcomes in mild stroke patients, save $200 million annually Feb 09, 2011 | not rated yet | 0
- Patients who wake up with stroke may be candidates for clot-busters Mar 12, 2009 | not rated yet | 0
- High blood pressure after stroke should not necessarily rule out use of clot-busting treatment Sep 08, 2008 | not rated yet | 0
- MRI may help determine time of stroke onset Nov 02, 2010 | not rated yet | 0
- Arrival method, slow response often delay stroke care Aug 08, 2008 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
The idea behind a reverse shock
2 hours ago So in a supernova explosion for example (5th slide) http://www.astro.princeton.edu/~burrows/classes/541/blastwavesChisari.pdf Ambient medium is...
Guass's Law for a charge distribution
3 hours ago First, this is not a homework question, just something I've been confused about for some time. I understand how to use Guass's law in many ways but...
3 hours ago Hello :) i'm new to this forum, so excuse me for my straightforwardness ;) I'm working on my bachelor work and i can't find a solution. I'm writing...
siphon and bernouli theorum
5 hours ago 1. I found this diagram on book but there weren't any description.can someone tell me, what its trying to tell specially by those two red lines...
Hot gas expansion rate into outer space
5 hours ago Good Morning Sirs, it seems to be surprisingly hard to get the numbers of a mystery: How fast expand hot rocket exhaust gases into empty space? ...
Magnetic field lines through copper
10 hours ago Hello. Assume an electron gun, as in CRT, made of plumbing copper instead of glass. Using magnetic scanning coils to move electron beam. Will the...
- More from Physics Forums - Classical Physics
More news stories
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
Cardiology 8 hours ago | not rated yet | 1
Mortality and length of stay are highest in heart failure patients admitted in January, on Friday, and overnight, according to research presented today at the Heart Failure Congress 2013. The analysis of nearly 1 million ...
Cardiology 8 hours ago | not rated yet | 0
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
Cardiology 8 hours ago | 5 / 5 (2) | 5
Transcatheter aortic valve implantation (TAVI) is effective and safe in Asian patients, according to early experience based on first results from a multicentre Asian registry reported at EuroPCR 2013.
Cardiology May 24, 2013 | not rated yet | 0
Routinely measuring fractional flow reserve (FFR) using pressure wire assessment during coronary angiography for diagnosis of chest pain leads to significant changes in the management of one in four patients, according to ...
Cardiology May 24, 2013 | not rated yet | 0
(HealthDay)—Animals make great companions for senior citizens, but elderly people who always drive with a pet in the car are far more likely to crash than those who never drive with a pet, researchers have ...
24 minutes ago | not rated yet | 0
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
8 hours ago | not rated yet | 0
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
May 20, 2013 | 4.8 / 5 (30) | 9 |
Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.
May 22, 2013 | 5 / 5 (4) | 6 |
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
May 24, 2013 | 4 / 5 (4) | 4 |
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
May 20, 2013 | 4.9 / 5 (7) | 5 |