GPs missing early dementia -- new study
New research from the University of Leicester demonstrates that general practitioners (GPs) are struggling to correctly identify people in the early stages of dementia resulting in both missed cases (false negatives) and misidentifications (false positives).
Researchers from the University of Leicester in the UK and National Collaborating Centre for Mental Health, London, UK and the Department of General Practice, Dusseldorf, Germany examined 30 previous studies involving 15,277 people seen in primary care for cognitive disorders, including 7109 assessed for dementia.
Although GPs managed to identify eight out of ten people with moderate to severe dementia, most patients with early dementia were not recognized. Only 45% of people with early dementia and mild cognitive impairment were identified. Mild cognitive impairment is a condition that may precede dementia in some people.
Across the whole spectrum, GPs identified 3 out of 5 of people attending for broadly defined memory problems.
Dr Alex Mitchell, a consultant psychiatrist with the Leicestershire Partnership NHS Trust and a researcher at the University, said: "This study highlights for the first time that GPs trying to identify dementia actually make more false positive errors, with misidentifications outnumbering missed cases at least two to one."
"GPs working in busy settings struggle to identify early dementia and prodromal conditions based on their initial clinical judgement. This was particularly the case for patients living alone where no informant was available and when patients had relatively preserved daily function. Furthermore, GPs' attitudes towards dementia may play an important role in dementia recognition. A project within the German Competence Network Degenerative Dementias (CNDD) at the University of Dusseldorf is currently investigating this.
"Conversely patients with depression or hearing problems were more at risk of being misidentified with dementia. However, the main influence is severity. Patients with mild dementia may not volunteer troubling memory problems and GPs are often unsure about the value of screening tests. Given the problem of false positives and false negatives we found that the application of a simple cognitive screening test after a clinical diagnosis would help GPs to achieve about 90% accuracy. We report separately which screening test may be best in Am J Geriatr Psychiatry 2010;18:759."
Provided by University of Leicester
- New research highlights dramatically reduced risk of developing dementia Mar 23, 2009 | not rated yet | 0
- Dementia screening in primary care: Is it time? Nov 27, 2007 | not rated yet | 0
- Education helps against dementia May 31, 2010 | not rated yet | 0
- Men more likely to have problems with memory and thinking skills Apr 16, 2008 | not rated yet | 0
- Study finds apathy and depression predict progression from mild cognitive impairment Jul 12, 2010 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
(HealthDay)—Few randomized clinical trials have been done to assess clinical prediction rules for patients with lower back pain, and the trials that have been done are of low quality and do not provide ...
Diseases, Conditions, Syndromes 12 hours ago | not rated yet | 0 |
A new, highly sensitive blood test that quickly detects even the lowest levels of malaria parasites in the body could make a dramatic difference in efforts to tackle the disease in the UK and across the world, according to ...
Diseases, Conditions, Syndromes 16 hours ago | not rated yet | 0
(AP)—The World Health Organization says a yellow fever booster vaccination given 10 years after the initial shot isn't necessary.
Diseases, Conditions, Syndromes 17 hours ago | not rated yet | 0
(AP)—Twenty-three youths have died in the past nine days at initiation ceremonies that include circumcisions and survival tests, South African police said Friday.
Diseases, Conditions, Syndromes 17 hours ago | 5 / 5 (1) | 2
The United States government public health agency, the CDC, pledges "To base all public health decisions on the highest quality scientific data, openly and objectively derived." But Peter Doshi, a postdoctoral fellow at Johns ...
Diseases, Conditions, Syndromes May 16, 2013 | not rated yet | 0
Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.
1 hour ago | not rated yet | 0
For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests
Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...
2 hours ago | not rated yet | 0 |
The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...
12 hours ago | not rated yet | 0 |
(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...
13 hours ago | 3.7 / 5 (3) | 0 |
In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...
10 hours ago | 3.7 / 5 (3) | 0 |
(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...
11 hours ago | 5 / 5 (2) | 0 |