Study finds pregnancy safe in multiple sclerosis
Canadian researchers have found that maternal multiple sclerosis (MS) is generally not associated with adverse delivery outcomes or risk to their offspring. Full findings now appear in Annals of Neurology, a journal published by Wiley-Blackwell on behalf of the American Neurological Association.
MS is a chronic, inflammatory neurologic disease and the most common cause of non-traumatic neurological disability in young adults in the Western world. Nearly 75% of MS patients are women who often experience disease onset in early adulthooda time when many consider starting a family. Prior studies report that up to one-third of women with MS bear children after disease onset, underscoring the need to understand the effects of maternal MS on pregnancy outcomes, which is the focus of the current study by Mia van der Kop, a member of the MS research group led by Dr. Helen Tremlett at the University of British Columbia and Vancouver Coastal Health Research Institute in Vancouver, Canada.
The research team analyzed data from the British Columbia (BC) MS Clinics' database and the BC Perinatal Database Registry between 1998 and 2009. Researchers identified 432 births to women with MS and 2975 to women without the disease, comparing gestational age, birth weight, type of birth (vaginal versus caesarean section). Age at MS onset, disease duration and level of disability were also examined.
Results showed that babies born to mothers with MS did not have a significantly different mean gestational age or birth weight compared to babies born to healthy mothers. Mothers with MS were not more likely to have a vaginal delivery or C-section. Researchers noted that MS mothers with greater levels of disability had a slightly elevated risk of adverse delivery outcomes. This finding was not statistically significant and further investigation was suggested. Age at onset of MS and duration of disease were not linked to adverse delivery or neonatal outcomes.
"Our finding that MS was not associated with poor pregnancy or birth outcomes should be reassuring to women with MS who are planning to start a family," said Dr. Tremlett. The authors did note that MS mothers were more often overweight or obese, which is associated with greater risk during pregnancy and birth. Researchers suggest that these women be advised to optimize their weight prior to becoming pregnant. "The importance of body mass index and pregnancy-related outcomes in MS should be explored in future studies," M. van der Kop concluded.
More information: "Neonatal and Delivery Outcomes in Women with Multiple Sclerosis"; Mia L. van der Kop, Mark S. Pearce, Leanne Dahlgren, Anne Synnes, Dessa Sadovnick, Ana-Luiza Sayao and Helen Tremlett. Annals of Neurology; Published Online: June 27, 2011 (DOI:10.1002/ana.22483).
Provided by Wiley
- Good news on multiple sclerosis and pregnancy Nov 18, 2009 | not rated yet | 0
- Can breastfeeding reduce multiple sclerosis relapses? Feb 19, 2009 | not rated yet | 0
- Men and women equally transmit genetic risk of MS to their children Jun 27, 2007 | not rated yet | 0
- Pregnancy in women with two types of MS may mitigate MS progression May 04, 2011 | not rated yet | 0
- Breastfeeding associated with a reduced risk of relapse in women with multiple sclerosis Jun 08, 2009 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Why is zone 1 in liver more prone to ischemic injury?
May 23, 2013 Hi, Is it because around central vein, there is only deoxygenated blood from the vein where as in the periphery there is hepatic artery. Also why...
How can there be villous adenoma in colon, if there are no villi there
May 22, 2013 As title suggest. Thanks :smile:
How can there be a term called "intestinal metaplasia" of stomach
May 21, 2013 Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
- More from Physics Forums - Medical Sciences
More news stories
New research presented today shows that formation of new neurons in the hippocampus - a brain region known for its importance in learning and remembering - could cause forgetting of old memories by causing a reorganization ...
Neuroscience 10 hours ago | 3.7 / 5 (3) | 0
How can healthy people who hear voices help schizophrenics? Finding the answer for this is at the centre of research conducted at the University of Bergen.
Neuroscience 10 hours ago | 4 / 5 (2) | 2
One of the major frontiers of modern science is a comprehensive understanding of the human brain and its functions to guide the development of new technologies in information and communication. In a major announcement for ...
Neuroscience 10 hours ago | 3 / 5 (2) | 0
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
Neuroscience May 23, 2013 | 4.9 / 5 (9) | 0 |
(Medical Xpress)—The human brain is able to identify individuals' voices by comparing them against an internal 'average voice' prototype, according to neuroscientists.
Neuroscience May 23, 2013 | 3 / 5 (2) | 3 |
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
4 hours ago | 5 / 5 (1) | 0 |
(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...
10 hours ago | 5 / 5 (3) | 0 |
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
7 hours ago | 5 / 5 (1) | 0 |
Talking on a hands-free device while behind the wheel can lead to a sharp increase in errors that could imperil other drivers on the road, according to new research from the University of Alberta.
4 hours ago | not rated yet | 0
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
7 hours ago | 5 / 5 (2) | 0 |
Kate O'Reilly's spring allergy survival kit includes the usual stuff - nasal sprays, allergy pills and a box of tissues. This season, she's added a new weapon to her line of defense: an app on her smartphone.
5 hours ago | not rated yet | 0