Low amounts of alcohol have different effects on left and right ventricles of the heart
Few studies have examined the acute effects of alcohol on myocardial or heart function. While moderate-to-high blood concentrations of alcohol acutely impair conventional echocardiographic measures of left ventricular (LV) performance, the effects of low concentrations are unclear. An examination of the acute effects of low blood concentrations of alcohol on the left and right ventricles, which collectively pump blood to the entire body, has found that low doses of alcohol can have very different effects on LV and right ventricular (RV) function.
Results will be published in the October 2011 issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View.
"Little data exist regarding the acute effects of alcohol on the heart," said Matteo Cameli, a cardiologist at the Cardiologia Universitaria of Siena as well as corresponding author for the study. "Previous studies have reported a reduction in LV performance after an assumption of moderate or high doses of alcohol, but the effects of low doses are still unknown."
Cameli explained that LV and RV function work very differently. "They are like two different worlds," he said, "both for structure and function of myocardial fibers that they present. Yet their differences, and the effects that low doses of alcohol have on them, have relevant social implications, given that light drinking is such a common practice."
Cameli and his colleagues asked 64 (35 men, 29 women) healthy volunteers in their twenties to drink, on two separate experiments, 5 ml/kg of Italian red wine (equivalent to 0.5 mg/kg of alcohol) and an equal volume of fruit juice. Study authors gathered a number of measures at baseline as well as 60 minutes following ingestion.
"We found that low doses of red wine is associated acute depression in left ventricular function and acute increase in right ventricular function," said Cameli. "These findings point out the importance of considering even low doses of alcohol as a socially relevant cause of acute cardiac toxicity because the truth is that light alcohol intoxication represents a very common occurrence worldwide."
Cameli added that this study is the first to examine the acute effects of low doses of red wine on cardiac performance through use of sensitive echocardiographic indices of cardiac function in a population of young healthy volunteers.
- Older adults more impaired by social drinking Mar 05, 2009 | not rated yet | 0
- Alcohol consumption may increase amphetamine abuse Dec 14, 2010 | not rated yet | 0
- Alcohol increases reaction time and errors during decision making Oct 19, 2010 | not rated yet | 0
- Light to moderate drinking linked to fewer heart problems in male bypass patients Nov 15, 2010 | not rated yet | 0
- One drug may help people both lay down the drink and put out the cigarette Mar 02, 2009 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
Talking on a hands-free device while behind the wheel can lead to a sharp increase in errors that could imperil other drivers on the road, according to new research from the University of Alberta.
Health 2 hours ago | not rated yet | 0
(HealthDay)—More than one in four of those eligible for new premium assistance tax credits under the Affordable Care Act (ACA) do not have a checking account and will not be able to receive premiums from ...
Health 4 hours ago | not rated yet | 0
After studying noise in one French Quarter neighborhood of New Orleans to determine whether or not noise levels exceeded municipal ordinances, Annette Hurley, PhD, Assistant Professor of Audiology at LSU Health Sciences Center ...
Health 5 hours ago | not rated yet | 0
Young children who missed more than half of recommended well-child visits had up to twice the risk of hospitalization compared to children who attended most of their visits, according to a study published today in the American Jo ...
Health 5 hours ago | not rated yet | 0
The individualisation of drug treatments to support patients to self-manage their conditions is a concept that sits at the heart of policy, but a recent study in BMJ Open shows that there is no concrete defini ...
Health 8 hours ago | 3 / 5 (1) | 0
(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...
8 hours ago | 5 / 5 (3) | 0 |
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
2 hours ago | 5 / 5 (1) | 0 |
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
5 hours ago | 5 / 5 (1) | 0 |
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
5 hours ago | 5 / 5 (2) | 0 |
(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...
23 hours ago | 4.9 / 5 (9) | 0 |
(Medical Xpress)—Patients with diabetes who are depressed are much more likely to develop episodes of dangerously low blood sugars, or hypoglycemia, than are those who are not depressed, a new study has ...
9 hours ago | not rated yet | 0 |