For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs
With 3,284 cycles using frozen eggs, Italy is the leader in Europe, the 27th Annual Meeting of the European Society of Human Reproduction and Embryology heard Wednesday.
Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births the lowest in the world and Spain's 30 % share of egg donations in Europe.
The EIM collected data on frozen oocyte retrieval (FOR) cycles for the first time. Until today, egg freezing is still not offered on a wide scale but can be an option for women who wish to postpone motherhood or are facing cancer therapy to save their lives. Recently, vitrification techniques have offered oocyte survival rates in excess of 90 % and implantation rates per transfer that are comparable with fresh eggs. Scientists still face problems such as poor oocyte survival post-thaw, low fertilisation rates, cytoskeletal damage during vitrification and poor reproducibility of results.
"Of the 19 countries reporting on FOR in 2008, Italy is by far the country with the most cycles using this technology," said Dr. Jacques de Mouzon, chair of the EIM. With 3,284 cycles, Italy is far ahead of Finland (325 cycles), Russia (220) and Spain (199). The reason for Italy's dominance in this area lies in its legislative framework. A law passed in 2004 and overruled in 2009, set a limit of three oocytes to be inseminated per cycle, of which all resulting embryos had to be transferred. Embryo freezing and research on the embryo was outlawed, but not egg freezing. Hence, Italian clinics gained considerable expertise in this area over the last years.
The group also reported that with 4,068 cycles, 30 % of all egg donations (ED) occur in Spain, followed by the Czech Republic (15 %) and Russia (12 %). "Three countries make up almost 60 % of all egg donations in Europe," said Dr. De Mouzon. "Certain clinics in Spain offer wide-ranging egg donation programmes, which may also be the reason why Spain scores so high in terms of frozen oocyte cycles." This fact is mostly due to restrictive laws on ED in many countries, leading to many couples to cross borders to countries with less restrictive laws, which has raised an ethical and public health problem.
During the same scientific session, Dr. Karl Nygren, chair of ICMART, presented global ART data for 2007. "We are particularly pleased to present our data in Stockholm this year, since we can show that Sweden, a pioneer in enforcing single embryo transfer, has the world's lowest multiple birth rate with only 7 % twins and 0.1% of triplets being born after IVF and ICSI." Only Finland and Australia show comparably low rates with 9.3 % and 8.4% of twins, respectively, and almost no triplets. Many countries are still above 20 % for twin deliveries following IVF or ICSI such as for example Spain (23.8 %), Italy (21.2 %) and Germany (21.1 %) as are many Eastern European countries. "We would like to see more countries follow suit to decrease long-term complications for mother and child." The average rate in Europe was 20.6 % for twins and 1.1% for triplets in Europe.
According to data presented by the European IVF Monitoring Group (EIM), 525,640 treatment cycles were reported in 36 European countries. Four more countries reported in 2008 compared to 2007. This compares globally with 148,055 cycles from the US and 61,929 cycles from Australia and New Zealand. "We observed a 9.7 % increase in the number of cycles in Europe from 2007 to 2008, with only 21 more clinics reporting to our database," said Dr. Jacques de Mouzon, chairman of ESHRE's EIM. The delivery rate (DR) per aspiration was 22.1% for IVF and 21.1% for ICSI. DR per transfer was 14.5% for FET and 28.5% for ED. All these rates were relatively stable compared to the previous year, as was the multiple deliveries proportion.
In 30 countries where clinics reported deliveries, 80,284 babies were born. "We believe this to be an underestimate since data on deliveries for Turkey, Poland and some other countries were still missing." There were 124,749 IVF treatments, 280,977 intracytoplasmic sperm injection (ICSI) cycles, 98,288 frozen embryo transfer cycles (FER), 13,609 egg donor cycles (ED), 4,080 FOR, 2,875 preimplantation genetic diagnosis/screening cycles (PGD/PGS) and 1,062 in vitro maturation cycles (IVM).
In terms of ART availability, the largest economies in Europe such as France (5,464 cycles per million women of reproductive age), Italy (4,015), Spain (3,845), the Netherlands (6,382), Germany (4,810) and the UK (4,066) still show much lower availabilities of ART compared to their Nordic neighbours such as Sweden (9,228), Norway (9,287), Denmark (12,712) and Finland (9,291). This is also mirrored in the number of infants born after ART with only 1.7 % in Spain, 2.4 % in the Netherlands, 1.4 % in Germany and 1.9 % in the UK compared to 3.3 % in Sweden, 2.4 % in Norway and 3.0 % in Finland. For Denmark figures were not available yet. Also, 25 countries reported 146,741 IUI-H (with husband's sperm) and 24, 895 IUI-D (donor sperm), with a multiple pregnancy rate (11.1% twin and 0.8 triplet for women aged less than 40 years) not higher than in IVF and ICSI.
Provided by European Society of Human Reproduction and Embryology
- Europe leads the world in assisted-reproduction technology Jun 30, 2010 | not rated yet | 0
- Worldwide report shows increase in assisted reproduction: 250,000 babies a year May 27, 2009 | not rated yet | 0
- ICSI or IVF: Babies born from frozen embryos do just as well Jun 29, 2009 | not rated yet | 0
- Children born from frozen embryos weigh more and do better than those born after fresh transfer Jul 08, 2008 | not rated yet | 0
- Single thawed embryo transfer after PGD does not affect pregnancy rates Jun 30, 2009 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
Marie Curie's leukemia
May 13, 2013 Does anyone know what might be the cause of Marie Curie's cancer
- More from Physics Forums - Medical Sciences
More news stories
In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual ...
Medical research 13 hours ago | 5 / 5 (3) | 0 |
In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...
Medical research May 17, 2013 | 4 / 5 (4) | 0 |
Scientists investigating the interaction of a group of proteins in the brain responsible for protecting nerve cells from damage have identified a new target that could increase cell survival.
Medical research May 17, 2013 | 5 / 5 (1) | 0
New findings by researchers carrying out experiments at the U.S. Department of Energy Office of Science's Advanced Photon Source (APS) help explain why some drugs that interact with two kinds of human serotonin ...
Medical research May 17, 2013 | 4 / 5 (1) | 0 |
Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, ...
13 hours ago | 4.8 / 5 (5) | 0 |
Researchers at the University of Wisconsin have identified a potential new risk factor for obstructive sleep apnea: asthma. Using data from the National Institutes of Health (Heart, Lung, and Blood Institute)-funded Wisconsin ...
12 hours ago | 5 / 5 (1) | 0 |
A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.
12 hours ago | 5 / 5 (2) | 0 |
The hunt for an HIV vaccine has gobbled up $8 billion in the past decade, and the failure of the most recent efficacy trial has delivered yet another setback to 26 years of efforts.
17 hours ago | not rated yet | 0
Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study from researchers at Columbia University shows purified components of the ...
12 hours ago | 5 / 5 (1) | 0
The devastating effect of Alzheimer's disease on bilingual people has been thrown into focus in Canada, where the sudden loss of a second language can leave sufferers feeling like strangers in their own country.
15 hours ago | not rated yet | 0