Team finds way to classify post-cardiac arrest patients to better predict outcomes

July 11, 2011

A new method for scoring the severity of illness for patients after cardiac arrest may help to predict their outcomes, according to researchers at the University of Pittsburgh School of Medicine. Most importantly, their findings, published in the early online version of Resuscitation, also show that none of the severity categories rules out the potential for a patient's recovery.

"Traditionally, we have used historical or event-related information, such as initial or whether someone witnessed the collapse, to categorize these patients upon arrival at the hospital," said Jon C. Rittenberger, M.D., lead author and assistant professor of . "Unfortunately, more than 10 percent of the time, such information is unavailable, which limits our ability to tailor therapies, counsel families about prognosis or select patients for clinical trials."

is the most common cause of death in North America, resulting in approximately 350,000 deaths each year.

The researchers looked at retrospective data for more than 450 post-cardiac arrest patients treated at UPMC Presbyterian between January 2005 and December 2009. Both in-hospital and out-of-hospital cardiac arrests were included. In 2007, the hospital implemented a multi-disciplinary post-cardiac arrest care plan, including therapeutic , or cooling of patients to minimize .

Four distinct categories of illness severity were identified based on a combination of neurological and cardiopulmonary dysfunction during the first few hours after restoration of a patient's spontaneous circulation. The researchers looked at rates of survival, neurologic outcomes and development of multiple for patients in each category, and found wide variations among the groups.

"Now, objective data available to the clinician at the bedside during initial evaluation may provide a better way of predicting outcomes and guiding the decisions of families and clinicians. We found that the category of illness severity had a stronger association with survival and good outcomes than did such historically used factors as initial rhythm of arrest or where it happened," said Dr. Rittenberger. "Our results indicate that illness severity should be carefully measured and accounted for in future studies of therapies for these patients."

Explore further: Black cardiac arrest patients more likely to be admitted to hospitals with lowest survival rates

Related Stories

Recommended for you

Female smokers face greatest risk for brain bleeds

July 21, 2016

Bleeding inside the lining of the brain (subarachnoid hemorrhage) is significantly more common among smokers, especially female smokers, than among people who do not smoke, according to new research in the American Heart ...

Global study shows stroke largely preventable

July 15, 2016

Ten risk factors that can be modified are responsible for nine of 10 strokes worldwide, but the ranking of those factors vary regionally, says a study led by researchers of the Population Health Research Institute (PHRI) ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.