New clinical study reveals statistically significant reduction in NICU infant mortality
In a long-running randomized study of over 3,000 preterm infants, those whose care included the Heart Rate Observation System, or HeRO monitor, experienced greater than 20 percent reduced mortality, effectively saving one infant's life for every 48 who were monitored. The results of this multicenter study of the HeRO monitor, co-sponsored by the National Institutes of Health and Medical Predictive Science Corporation (MPSC), appear in The Journal of Pediatrics.
HeRO is a pioneering monitoring system for premature infants that detects early signs of distress, commonly caused by infection and other potentially life-threatening illnesses. HeRO generates an hourly numeric score that quantifies the prevalence of abnormal patterns in each patient's heart rate and provides a new tool for clinical assessment so that standard diagnostic and therapeutic decisions are better founded.
The study, "Mortality reduction by heart rate characteristic monitoring in very low birth weight neonates: a randomized trial," was conducted from April 2004 to September 2010 at leading neonatal intensive care units (NICU) at the University of Virginia, Wake Forest University, University of Alabama at Birmingham, Vanderbilt University, University of Miami/Jackson Memorial Hospital, Greenville SC Hospital System, Winnie Palmer Children's Hospital and Pennsylvania State University.
There were 152 deaths (10.2 percent) in the group that received standard NICU care and 122 deaths (8.1 percent) in the group that received standard NICU care plus HeRO monitoring, an absolute risk reduction of 2.1 percent. There were no significant differences in demographics between the two groups, nor any of the other outcomes measured by the study.
The study's lead investigator and co-inventor J. Randall Moorman, M.D., a University of Virginia cardiologist said, "The HeRO monitor is the voice for infants who can't speak for themselves. It's an early warning system for NICU doctors and nurses to get to the right bedside at the right time."
According to the March of Dimes, about 12.8 percent of babies (more than half a million a year) in the U.S. are born prematurely and the rate of premature birth has increased by 36 percent since the early 1980s. Among the 60,000 premature babies born less than 3.3 pounds each year, the mortality rate is approximately 10 percent.
The results of the study point to the possibility of saving the lives of an additional 1,200 premature babies each year.
Provided by Environics
- Neonatal intensive care units critical to infant survival Sep 01, 2010 | not rated yet | 0
- Preterm birth contributes to growing number of infant deaths Jul 29, 2008 | not rated yet | 0
- Nearly 28,000 US infants died in 2004 May 04, 2007 | not rated yet | 0
- More babies born prematurely, new report shows Dec 06, 2007 | not rated yet | 0
- Care of late-preterm preemies may be insufficient Jan 03, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
Vermont became on Monday the third US state to legalize physician-assisted suicide.
Other 10 hours ago | not rated yet | 0
Food microbiology laboratories continue to submit false negative results and false positive results on a routine basis. A retrospective study of nearly 40,000 proficiency test results over the past 14 years, presented today ...
Other 15 hours ago | not rated yet | 0
Siemens has presented the world's first ultrasound system with wireless transducers. The system's transducers, which can be easily operated with one hand, transmit ultrasound images via radio waves to the ...
Other 19 hours ago | not rated yet | 0
(AP)—A woman who lost both hands, her left leg and right foot after contracting a flesh-eating disease has been fitted with prosthetic hands.
Other May 18, 2013 | not rated yet | 0
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
9 hours ago | 4.6 / 5 (12) | 4 |
Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincinnati Children's Hospital ...
3 hours ago | not rated yet | 0 |
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
12 hours ago | 4.8 / 5 (11) | 2 |
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
12 hours ago | 4.8 / 5 (6) | 2 |
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...
12 hours ago | 5 / 5 (3) | 0 |
Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio, the online open-access journal of the American Society for Microb ...
3 hours ago | 5 / 5 (1) | 0