Researchers use improved imaging technique; discover a better approach to diagnosing epilepsy

August 1, 2011

Using state-of-the-art, 7 Tesla magnetic resonance imaging (MRI) technology, University of Minnesota Medical School researchers may have uncovered a better approach to diagnosing epilepsy.

In the process, the team was able to cure eight patients of all epileptic symptoms.

Epilepsy, a neurological disorder causing repeated seizures or convulsions, impacts about one percent of the population, according to the National Institutes of Health (NIH). The most common type of epilepsy is , caused by scarring inside the hippocampus, a major memory center of the brain. Many of these patients have severe memory problems, even in between seizures.

Using 7 Tesla MRI technology, a U of M research team led by University of Minnesota Physician neurologist Dr. Thomas Henry, scanned epileptic patients to capture extremely detailed images of their brain. (The strength of a magnetic field is measured in Tesla units. The higher the field strength, the more detailed the image acquired by MRI machines.)

While most standard clinical have strength of 1.5 or 3 Tesla, the improved 7 Tesla technology allowed researchers to make highly-improved, detailed images of patients' , especially the portion responsible for causing epilepsy.

The clearer allowed Henry and his colleagues to more accurately find associated with temporal lobe epilepsy. Accurately locating this scarring is critical because if medications fail to control , it's often possible for highly-trained neurosurgeons to remove scars from the brain in order to stop the seizures. The healthy parts of the brain left untouched, and actually begin to function better after seizures stop.

"There is huge potential here to improve patient care through improved approaches to ," Henry said. "When you see how much clearer these 7 Tesla images are, compared with standard MRI, it's sort of like reading fine print with a magnifying glass versus the naked eye. The possibility of using 7 Tesla MRI to find brain lesions that were missed on current brain scans is likely to be very helpful in epilepsy and many other conditions."

Dr. Henry and his team conducted their research in the University of Minnesota's Center for Research (CMRR), an interdisciplinary research laboratory that is home to the world's strongest imaging magnets and most sensitive scanners.

"Standard MRI technology is an effective way to diagnose epilepsy when it is caused by large lesions," said Henry. "We believe that by using 7 Tesla machines, which we have right at our fingertips on the University of Minnesota campus, we'll be able to treat a greater population of epileptic patients more effectively," said Henry.

Related Stories

Recommended for you

High-fat diet starves the brain

April 29, 2016

A high-fat diet of three days in mice leads to a reduction in the amount of glucose that reaches the brain. This finding was reported by a Research Group led by Jens Brüning, Director at the Max Planck Institute for Metabolism ...

A vitamin that stops the aging process of organs

April 28, 2016

Nicotinamide riboside (NR) is pretty amazing. It has already been shown in several studies to be effective in boosting metabolism. And now a team of researchers at EPFL's Laboratory of Integrated Systems Physiology (LISP), ...

Lifestyle has a strong impact on intestinal bacteria

April 28, 2016

Everything you eat or drink affects your intestinal bacteria, and is likely to have an impact on your health. That is the finding of a large-scale study led by RUG/UMCG geneticist Cisca Wijmenga into the effect of food and ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.