Poor sleep quality increases risk of high blood pressure
Reduced slow wave sleep (SWS) is a powerful predictor for developing high blood pressure in older men, according to new research in Hypertension: Journal of the American Heart Association.
SWS, one of the deeper stages of sleep, is characterized by non-rapid eye movement (non-REM) from which it's difficult to awaken. It's represented by relatively slow, synchronized brain waves called delta activity on an electroencephalogram. Researchers from the Outcomes of Sleep Disorders in Older Men Study (MrOs Sleep Study) found that people with the lowest level of SWS had an 80 percent increased risk of developing high blood pressure.
"Our study shows for the first time that poor quality sleep, reflected by reduced slow wave sleep, puts individuals at significantly increased risk of developing high blood pressure, and that this effect appears to be independent of the influence of breathing pauses during sleep," said Susan Redline, M.D., the study's co-author and Peter C. Farrell Professor of Sleep Medicine in the Department of Medicine at Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School in Boston, Mass.
Men who spent less than 4 percent of their sleep time in SWS were significantly more likely to develop high blood pressure during the 3.4 years of the study. Men with reduced SWS had generally poorer sleep quality as measured by shorter sleep duration and more awakenings at night and had more severe sleep apnea than men with higher levels of SWS. However, of all measures of sleep quality, decreased SWS was the most strongly associated with the development of high blood pressure. This relationship was observed even after considering other aspects of sleep quality.
Participant's average body mass index was 26.4 kg/m2. But the study effects of SWS were independent of obesity and continued to be seen after considering the effects of obesity.
The researchers conducted comprehensive and objective evaluation of sleep characteristics related to high blood pressure in 784 men who didn't have hypertension. They were studied in their own homes using standardized in-home sleep studies, or polysomnography, with measurement of brain wave activity distinguishing between REM and non-REM sleep, and sleep apnea through measurement of breathing disturbances and level of oxygenation during sleep.
Using a central Sleep Reading Center directed by Redline, the researchers assessed a wide range of measurements of sleep disturbances, such as frequency of breathing disturbances, time in each sleep state, number of nighttime awakenings, and sleep duration.
The participants were an average 75 years old and almost 90 percent were Caucasian. All were healthy and living in one of six communities, geographically representative of the United States: San Diego, Calif.; Palo Alto, Calif.; Pittsburgh, Pa.; Minneapolis, Minn.; Birmingham, Ala.; and Portland, Oregon. The study was coordinated by California Pacific Medical Center.
Generally, older men and women are more likely to develop high blood pressure than younger people. Sleep disorders and poor quality sleep are more common in older adults than in younger ones. Obesity is also associated with hypertension, researchers said.
In the Sleep Heart Health Study, another large cohort study, researchers found that men were more likely to have less SWS than women. Men were also at an increased risk of high blood pressure when compared to women. The current study raises the possibility that poorer sleep in men may partly explain the male gender predisposition to high blood pressure.
"Although women were not included in this study, it's quite likely that those who have lower levels of slow wave sleep for any number of reasons may also have an increased risk of developing high blood pressure," Redline said.
Slow wave sleep has been implicated in learning and memory with recent data also highlighting its importance to a variety of physiological functions, including metabolism and diabetes, and neurohormonal systems affecting the sympathetic nervous system that contribute to high blood pressure, researchers said.
Good quality sleep is the third pillar of health, Redline said. "People should recognize that sleep, diet and physical activity are critical to health, including heart health and optimal blood pressure control. Although the elderly often have poor sleep, our study shows that such a finding is not benign. Poor sleep may be a powerful predictor for adverse health outcomes. Initiatives to improve sleep may provide novel approaches for reducing hypertension burden."
Provided by American Heart Association
- Study examines ethnic differences in sleep quality and blood pressure Oct 29, 2007 | not rated yet | 0
- Poor teen sleep habits may raise blood pressure, lead to CVD Aug 18, 2008 | not rated yet | 0
- Child sleep breathing problems studied Oct 09, 2006 | not rated yet | 0
- Less sleep associated with high, worsening blood pressure in middle age Jun 08, 2009 | not rated yet | 0
- Researchers Identify Connection between Sleep Disruption and Increased Cardiovascular Risk Mar 30, 2007 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Change in momentum when a body is thrown up and falls back down.
6 hours ago Say, a body of mass 'm' is thrown at a certain angle with the vertical with certain initial velocity 'u'. The initial momentum of this object is mu....
change in speed and wavelength of light while travelling from one med
7 hours ago what is the mechanism by which light changes its speed and wavelength while travelling from one medium to other. I know it is c/n or lamda/n and know...
Calculus of Variation - Classical Mechanics
9 hours ago I'm reading Classical Mechanics (Taylor), and the 6th chapter is a basic introduction to calculus of variations. I'm super confused :confused: ...
Frictional Force Equation Doesn't Make Sense
10 hours ago Frictional Force is mathematically defined as: Ff = μ*m*g*cos(θ) , where μ is the coefficient of friction, m is the mass of the object, g is...
Calculating Steam Pressure in Closed Container
15 hours ago I am trying to calculate the volume of liquid water i need to place in a sealed container in order to obtain 10 psi of steam pressure in that closed...
Learning curve of Electromagnetism?
20 hours ago I'm taking a first year physics course and have been having a little trouble with the basics of newtons laws and forces and whatnot, though nothing...
- More from Physics Forums - Classical Physics
More news stories
We're told to have power naps to keep us safe on the road and improve our alertness if we've had insufficient sleep. They even help our surgeons stay awake during long shifts. But siestas and nana naps can ...
Sleep apnea May 17, 2013 | 5 / 5 (3) | 1
(HealthDay)—The widening American waistline may be feeding an epidemic of sleep apnea, potentially robbing millions of people of a good night's rest, a new study suggests.
Sleep apnea May 10, 2013 | not rated yet | 0
A new study suggests that regularity of bedtime prior to initiation of continuous positive airway pressure (CPAP) therapy is an important factor that may influence treatment compliance in adults with obstructive sleep apnea ...
Sleep apnea May 07, 2013 | 5 / 5 (1) | 0
A new study suggests that obstructive sleep apnea severity is higher in African-American men in certain age ranges, even after controlling for body mass index (BMI).
Sleep apnea Apr 12, 2013 | 5 / 5 (2) | 0
People with sleep apnoea are more likely to fail a driving simulator test and report nodding whilst driving, according to new research.
Sleep apnea Apr 11, 2013 | not rated yet | 0
The devastating effect of Alzheimer's disease on bilingual people has been thrown into focus in Canada, where the sudden loss of a second language can leave sufferers feeling like strangers in their own country.
3 minutes ago | not rated yet | 0
The hunt for an HIV vaccine has gobbled up $8 billion in the past decade, and the failure of the most recent efficacy trial has delivered yet another setback to 26 years of efforts.
1 hour ago | not rated yet | 0
Regular consumption of coffee is associated with a reduced risk of primary sclerosing cholangitis (PSC), an autoimmune liver disease, Mayo Clinic research shows. The findings were being presented at the Digestive Disease ...
9 hours ago | not rated yet | 0 |
Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the ...
9 hours ago | 4.7 / 5 (3) | 0 |
Research presented at Digestive Disease Week (DDW) explores new methods for managing digestive health through diet and lifestyle.
9 hours ago | not rated yet | 1
An increasing number of U.S. children are experiencing gastrointestinal issues that require interventions to resolve, according to research presented at Digestive Disease Week (DDW).
May 18, 2013 | not rated yet | 0 |