Treatment of CV risk factors appears to improve sexual function in men with erectile dysfunction

September 12, 2011

Lifestyle modifications and pharmaceutical treatment of risk factors for cardiovascular disease are associated with improvement in sexual function among men with erectile dysfunction (ED), according to a meta-analysis posted Online First today in Archives of Internal Medicine.

"Erectile dysfunction shares modifiable risks factors with atherosclerosis and (CAD), including hypertension, diabetes, dyslipidemia, cigarette smoking, obesity, metabolic syndrome, and sedentary behavior," according to background information in the article. "Erectile dysfunction has a high prevalence in individuals with multiple cardiovascular (CV) risk factors and is an independent predictor or CV events and may serve as the sentinel marker for CV disease (CVD)."

Bhanu P. Gupta, M.D., and colleagues with the Mayo Clinic, Rochester, Minn., conducted a meta-analysis of six previous from four countries to evaluate the effects of and pharmaceutical treatment of on the severity of ED.

The six trials examined in the meta-analysis included a total of 740 participants, with the number of participants per trial ranging from 12 to 372. Average age of the participants was 55.4 years and the study duration ranged from 12 to 104 weeks. All studies included in the analysis showed improvement in ED with lifestyle changes and improvement in parameters.

The authors found that improvement in CV risk factors was associated with statistically significant improvement in sexual function in men with ED. When trials using pharmaceutical treatment were excluded and only studies using lifestyle interventions were examined, the improvement in sexual function was still statistically significant. Pharmaceutical treatment targeting CV risk factors also demonstrated improvement in sexual function.

"In summary, this study further strengthens the evidence of improvement in ED and maintenance of sexual function with lifestyle intervention and CV risk factor reduction," the authors write. "Men with ED provide an opportunity to identify CV risk factors and initiate lifestyle changes."

Explore further: Erectile dysfunction influenced by race and ethnicity

More information: Arch Intern Med. Published online September 12, 2011. doi:10.1001/archinternmed.2011.440

Related Stories

Erectile dysfunction influenced by race and ethnicity

January 31, 2007

According to a new study in The Journal of Sexual Medicine, erectile dysfunction (ED) is highly prevalent across white, black and Hispanic populations in the United States. For the first time in an adequately-sized, nationally ...

Recommended for you

Bacteria in smokeless tobacco products may be a health concern

August 26, 2016

Several species of bacteria found in smokeless tobacco products have been associated with opportunistic infections, according to a paper published August 26 in Applied and Environmental Microbiology, a journal of the American ...

Is tailgating toxic?

August 26, 2016

While tailgating this football season you may want to take a step back from the grill and generator—for your health.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.