New technology offers the next generation of mammography

October 1, 2011 in Cancer

Breast cancer is the second most common type of cancer among women in the United States, with approximately 200,000 new diagnoses each year. Early detection is key in the treatment of breast cancer and the biggest advancement for detection in 30 years has arrived at University Hospitals (UH) Case Medical Center – tomosynthesis, an innovative technology that provides three-dimensional detailed imaging of the breast.

"Tomosynthesis offers women the next generation in breast cancer detection," says Donna Plecha, MD, Director of Breast Imaging at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine. "This revolutionary technology provides exceptionally sharp images and is an important new tool in our arsenal to detect breast cancer early when it is treatable."

Breast cancer is a significant health problem and statistics indicate that one in eight women will develop the disease in her lifetime. The stage at which the cancer is discovered influences a woman's chance of survival and annual mammography after the age of 40 enables physicians to identify the smallest abnormalities. In fact, when breast cancer is detected early and confined to the breast, the five-year survival rate is 97 percent.

"Annual screening mammograms starting at the age of 40 saves lives," says Paula Silverman, MD, Medical Director of the Breast Cancer Program, Seidman Cancer Center at UH Case Medical Center and Associate Professor at Case Western Reserve School of Medicine. "Breast cancers caught in the initial stages by mammography are more likely to be cured and are less likely to require chemotherapy or as extensive surgery."

University Hospitals was involved with early studies of tomosynthesis and now patients at the Breen Breast Health Pavilion at UH Case Medical Center in Cleveland's University Circle and UH Chagrin Highlands Health Center in Orange Village, Ohio, are among the first in the nation to be offered the system. UH uses the Selenia® Dimensions® 3D digital mammography system, manufactured by Hologic and recently approved by the FDA, combining advanced digital mammography and tomosynthesis-generated images to provide a more detailed, highly focused picture of the breast.

The system acquires multiple, low-dose images at different angles, similar to Computed Tomography (CT) of the body. These images are then used to produce a series of one-millimeter thick slices that can be viewed as a 3D reconstruction of the breast. Women getting a mammogram will not feel any difference on the new machines. The tomosynthesis unit looks similar to the previous mammogram machines and the amount of breast compression is identical to the conventional mammogram.

The technology gives radiologists the ability to identify and characterize individual breast structures and clearly see features which might be obscured in a traditional two-dimensional mammogram by overlapping normal breast anatomy that may mimic or mask a tumor. Dense tissue and overlapping tissue structures may lead to false positive or false negative results with standard .

Tomosynthesis additionally has the potential to decrease the number of women who need to return for additional testing. Nationally, about 10 percent of women who undergo a regular screening mammogram are recalled for additional mammogram images after an abnormality is detected which can be very stressful.

"This cutting edge technology helps radiologists detect, screen and find breast cancers at very early stage tumors when they're small," adds Dr. Plecha. "It also helps us to pinpoint the location, size and shape of the cancer. Our only and best defense against is catching it early and curing it at a more treatable stage and tomosynthesis provides us with an important new tool to decrease cancer mortality and save lives."

More information: To view a UH news video about tomosynthesis, go to: http://www.uhhospi … omosynthesis

Provided by University Hospitals Case Medical Center

not rated yet  

Rank not rated yet
Relevant PhysicsForums posts
  • Potential Breakthrough in Seizure Control
    created11 hours ago
  • Popping/Cracked sternum.
    created16 hours ago
  • Which Mental Illness Encompasses This Problem?
    created16 hours ago
  • A question about drug tolerance
    createdMay 23, 2012
  • Poor nutrition leading to overeating?
    createdMay 23, 2012
  • Math and dyslexia?
    createdMay 21, 2012
  • More from Physics Forums - Medical Sciences

More news stories

Skp2 activates cancer-promoting, glucose-processing Akt

HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

Cancer created May 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

Pancreatectomy OK without downstaging from therapy

(HealthDay) -- Pancreatectomy improves median survival in pancreatic cancer patients even when presurgical neoadjuvant therapy does not lead to radiographic downstaging of tumors, according to a study published ...

Cancer created May 25, 2012 | popularity not rated yet | comments 0

Common therapies for basal cell carcinoma offer similar survival

(HealthDay) -- For patients with superficial basal cell carcinoma (sBCC), treatment with imiquimod or photodynamic therapy (PDT) results in similar long-term tumor-free survival, according to a review published ...

Cancer created May 25, 2012 | popularity not rated yet | comments 0

Cancer may require simpler genetic mutations than previously thought

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...

Cancer created May 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

New prostate cancer screening guidelines face a tough sell, study suggests

(Medical Xpress) -- Recent recommendations from the U.S. Preventive Services Task Force (USPSTF) advising elimination of routine prostate-specific antigen (PSA) screening for prostate cancer in healthy men are likely to encounter ...

Cancer created May 25, 2012 | popularity not rated yet | comments 1


Travel to high altitudes tied to Crohn's, colitis flare-ups

(HealthDay) -- People with inflammatory bowel disease, which includes Crohn's disease and colitis, may be at increased risk for flare-ups when they fly or travel to high altitudes for skiing or mountain climbing, ...

Family history of Alzheimer's affects functional connectivity

(HealthDay) -- Cognitively normal individuals with a family history of late-onset Alzheimer's disease (AD) may display lower resting state functional connectivity in the default mode network (DMN) of the brain, ...

Transvaginal mesh op restores pelvic organ prolapse at price

(HealthDay) -- Transvaginal mesh (TVM) procedures are effective for anatomical restoration of pelvic organ prolapse (POP), but patients report a worsening of sexual function following surgery, according to ...

Tongue analysis software uses ancient Chinese medicine to warn of disease

For 5,000 years, the Chinese have used a system of medicine based on the flow and balance of positive and negative energies in the body. In this system, the appearance of the tongue is one of the measures used to classify ...

Of mice and mental models: Neuroscientific implications of risk-optimized behavior in the mouse

(Medical Xpress) -- Regardless of an organism’s biological complexity, every encephalized animal continuously makes under-informed behavioral choices that can have serious consequences. Despite its ubiquity, ...

Weight struggles? Blame new neurons in your hypothalamus

New nerve cells formed in a select part of the brain could hold considerable sway over how much you eat and consequently weigh, new animal research by Johns Hopkins scientists suggests in a study published in the May issue ...