Bioengineering yields new approaches for diagnosing and treating traumatic brain injury

Journal of Neurotrauma is an authoritative peer-reviewed journal published monthly in print and online that focuses on the latest advances in the clinical and laboratory investigation of traumatic brain and spinal cord injury. Emphasis is on the basic pathobiology of injury to the nervous system, and the papers and reviews evaluate preclinical and clinical trials targeted at improving the early management and long-term care and recovery of patients with traumatic brain injury. Credit: Copyright Mary Ann Liebert, Inc., publishers

Bioengineering -- the application of engineering principles to understand and treat medical conditions -- is delivering innovative solutions for diagnosing and repairing damage to the brain caused by a traumatic injury. A broad sample of these new, cutting-edge techniques is presented in a special issue of Journal of Neurotrauma, a peer-reviewed journal published by Mary Ann Liebert, Inc.

The issue captures the broad scope of current and future diagnostic and therapeutic strategies being developed based on novel biomaterials, innovative applications of biomechanics, and advanced simulation and computational technology. Guest Editors Michelle C. LaPlaca, PhD, Associate Professor of Biomedical Engineering, Georgia Tech College of Engineering, and David F. Meaney, PhD, Associate Director, Penn Center for and Repair, and Professor and Chair, Department of Bioengineering, University of Pennsylvania, have compiled a fascinating collection of articles that describe leading research in the areas of three-dimensional cell and tissue preparations designed to study the effects of and to stimulate , computer modeling, and novel imaging and analytical techniques being applied to advance neurotrauma research and patient care.

Original research articles featured in this issue of include "A Detailed Viscoelastic Characterization of the P17 and Adult Rat Brain," by Benjamin Elkin et al.; "Survival Risk Assessment for Primary Blast Exposures to the Head," by Karin Rafaels and colleagues; and "Toward a Convergence of Regenerative Medicine, Rehabilitation, and Neuroprosthetics," by Shyam Aravamudhan et al.

"The Journal is pleased to publish this issue which addresses many of the bioengineering advances being made in the field of injury. Further, this compendium of manuscripts emphasizes the important, yet underappreciated, fact that biomechanical-induced change distinguishes CNS trauma from all other CNS disorders," says John T. Povlishock, PhD, Editor-in-Chief of Journal of Neurotrauma and Professor, VCU Neuroscience Center, Medical College of Virginia, Richmond.

More information: The entire issue is available online at http:// www.liebertpub.com/neu

Provided by Mary Ann Liebert, Inc.

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