New tuberculosis research movement needed

November 30, 2011

In this week's PLoS Medicine, Christian Lienhardt from the WHO in Geneva, Switzerland and colleagues announce that the Stop TB Partnership and the WHO Stop TB Department have launched the TB Research Movement.

In the article the authors describe the development of the Research Movement strategic plan, highlighting progress in its two key components: (1) the analysis of the global funding landscape for TB research, and (2) the development of a global TB research agenda.

The problem remains vast. The authors say that "With 9.4 million new cases of tuberculosis (TB) and 1.7 million TB deaths worldwide in 2009, TB constitutes an unacceptable burden of human suffering and loss. The tools available for are old, lack effectiveness, and are not readily accessible in many settings: the diagnosis of still relies in most high-burden countries on sputum microscopy, a century old technology; treatment of tuberculosis is based on drugs that are over 40 years old and requires direct supervision to ensure full treatment adherence and prevent ; and the only (BCG), first used in 1922, has a variable protective efficacy in adults. Novel tools are needed for better TB care and control worldwide."

The authors go on: "Through this strategic plan, the TB research movement is creating a framework for concrete actions to harmonize and synergize TB research efforts globally, so that the poor and vulnerable populations burdened by TB will reap the dividend of less TB through more research and innovation."

More information: Lienhardt C, Espinal M, Pai M, Maher D, Raviglione MC (2011) What Research Is Needed to Stop TB? Introducing the TB Research Movement. PLoS Med 8(11): e1001135. doi:10.1371/journal.pmed.1001135

Related Stories

Recommended for you

Experimental MERS vaccine shows promise in animal studies

July 28, 2015

A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines. ...

Can social isolation fuel epidemics?

July 21, 2015

Conventional wisdom has it that the more people stay within their own social groups and avoid others, the less likely it is small disease outbreaks turn into full-blown epidemics. But the conventional wisdom is wrong, according ...

Lack of knowledge on animal disease leaves humans at risk

July 20, 2015

Researchers from the University of Sydney have painted the most detailed picture to date of major infectious diseases shared between wildlife and livestock, and found a huge gap in knowledge about diseases which could spread ...

IBD genetically similar in Europeans and non-Europeans

July 20, 2015

The first genetic study of inflammatory bowel disease (IBD) to include individuals from diverse populations has shown that the regions of the genome underlying the disease are consistent around the world. This study, conducted ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.