Mayo Clinic makes kidney and pancreas transplant available to HIV-infected patients

Mayo Clinic in Florida is now offering kidney and pancreas transplants to HIV positive patients with advanced kidney disease and diabetes. Evidence is now solid that HIV-positive patients have the same favorable outcome in terms of patient and allograft survival as non-HIV positive organ transplant recipients, says Mary Prendergast, M.D., a kidney specialist whose focus is the care of patients who receive kidney and pancreas transplants.

"With the utilization of HAART therapy to control HIV disease, it is very clear that solid organ transplant is both feasible and successful," she says. "We are very excited to be able to offer this service, which will provide end-stage kidney disease patients an alternative to years of difficult ."

Concerns in the past relating to the necessity of utilizing anti-rejection medications to transplant already immunosuppressed HIV-positive patients have been overcome with solid evidence that there is no increase in either the incidence of opportunistic infection or an acceleration of HIV disease, Dr. Prendergast says, as demonstrated in a recent large multi-center U.S.-based study, published last November in The .

Mayo Clinic in Florida has offered liver transplant for HIV-positive patients for a number of years now Dr. Prendergast says, and currently performs approximately 110 kidney transplants each year, and 10 pancreatic transplants, either alone or in combination, for non-HIV patients. Criteria for transplantation in HIV positive patients include an undetectable viral load and CD4 count greater than 200 cells per cubic millimeter, she says. Patients will be eligible to receive both deceased and living donor transplant organs.

The need for organ transplants is widespread, Dr. Prendergast adds. Currently there are 96,000 patients on the and 1,300 waiting for a wait lists, according to the United Network for Organ Sharing (UNOS). Between one and three percent of those on dialysis are HIV positive.

add to favorites email to friend print save as pdf

Related Stories

Could HIV-infected organs save lives?

Mar 30, 2011

If Congress reversed its ban on allowing people with HIV to be organ donors after their death, roughly 500 HIV-positive patients with kidney or liver failure each year could get transplants within months, rather than the ...

Most kidney transplant candidates will accept risk of infection

Mar 25, 2010

Most kidney transplant candidates are willing to receive a kidney from a donor at increased risk of viral infection, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN ...

Recommended for you

Amgen misses 1Q views as higher costs cut profit

Apr 22, 2014

Despite higher sales, biotech drugmaker Amgen's first-quarter profit fell 25 percent as production and research costs rose sharply, while the year-ago quarter enjoyed a tax benefit. The company badly missed ...

Valeant, Ackman make $45.6B Allergan bid

Apr 22, 2014

Valeant Pharmaceuticals and activist investor Bill Ackman have unveiled details of their offer to buy Botox maker Allergan, proposing a cash-and-stock deal that could be worth about $45.6 billion.

User comments