Inflammatory bowel disease emerges as a global disease
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing with time and in different regions around the world, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.
"Insight into the worldwide epidemiology of inflammatory bowel disease is important for the identification of geographic patterns and time trends," said Gilaad G. Kaplan, MD, MPH, of the University of Calgary and lead author of this study. "Our findings will help researchers estimate the global public health burden of inflammatory bowel disease so that appropriate health-care resources are allocated, and targeted research is conducted in specific geographic regions," added Dr. Kaplan, an Alberta Innovates Health Solutions population health investigator. View a video in which he discusses the study's findings and implications, and a patient recalls his experiences with Crohn's disease, a major illness recognized most often as IBD.
This video is not supported by your browser at this time.Population-based epidemiologic data of IBD collected in a standardized fashion in developing nations are sparse. To properly interpret the incidence or prevalence data and evaluate time trends, researchers conducted a systematic review of all population-based studies that describe the incidence and/or prevalence of IBD. They found that the incidence of IBD is increasing or stable in virtually every region of the world that has been studied.
Researchers found that the highest prevalence of IBD worldwide was reported in Canada and Europe, whereas Asia had a lower prevalence of IBD. In developing nations, IBD was a rare occurrence; however, as these nations have become more industrialized, the incidence of IBD has increased. Gender differences were inconsistent, suggesting that the disease occurred equally among females and males.
Universally, incidence rates for both Crohn's disease and ulcerative colitis were highest among individuals who were between 20 and 40 years old. Thus, IBD affects individuals in the most healthy and productive years of life, resulting in long-term cost to the patient, health-care system and society.
Despite more than 200 publications in the literature on IBD, this study highlights the need for incidence and prevalence data in many regions of the world, particularly from developing countries. Future studies in these regions are required to provide important insights into the etiology of IBD.
The two major illnesses that are recognized most often as inflammatory bowel disease are ulcerative colitis and Crohn's disease. The most common symptoms of ulcerative colitis, which occurs in the inner lining of the colon (large intestine) or rectum, are diarrhea, abdominal cramps and rectal bleeding. Patients suffering from Crohn's disease, an inflammation and ulceration process that occurs in the deep layers of the intestinal wall, experience pain in the abdomen often in the lower right side diarrhea, weight loss and occasionally bleeding.
Provided by American Gastroenterological Association
- Distinct demographic profiles between Crohn's disease and ulcerative colitis Feb 05, 2010 | not rated yet | 0
- Vitamin D deficiency puts IBD patients at greater risk of osteoporosis Oct 18, 2010 | not rated yet | 0
- Study reveals possible link between IBD therapy and skin cancer Oct 26, 2009 | not rated yet | 0
- Bacteria identified that may lead to inflammatory bowel disease in certain individuals Sep 16, 2010 | not rated yet | 0
- Doctors see more children with inflammatory bowel disease Mar 29, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Assumptions of Griffith's fracture theory
6 hours ago Any experts on Griffith's fracture theory? I am studying the subject and I am having hard time finding out if the theory is valid for all possible...
Current leading voltage or vice versa concept
7 hours ago Hello, I was wondering if there is a conceptual explanation for when current leads voltage or vice versa for capacitors or inductors with AC...
Angular Frequency of AC voltage
10 hours ago Hello, I am wondering, what is the physical interpretation of the angular frequency of AC voltage? I don't see the physicality of what the angle...
Modeling Rigid Body - Unsure about Euler angles and angular velocity
11 hours ago I'm modeling a single 3D rigid body in preparation for some more complicated modeling in order to gain a better understanding of Euler angles, the...
Function for a bullet's path
12 hours ago I've been mulling this over all weekend, and I've decided to get some help on this. The problem is writing a function to describe a bullet's path....
Elementary questions relating to Newton's laws of motion
14 hours ago i) If a wall breaks when it gets hit by a cannonball, did the wall exert an equal and opposite force on the cannonball? ii) Would the force...
- More from Physics Forums - Classical Physics
More news stories
Patients with inflammatory bowel disease (IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. ...
Inflammatory disorders 23 hours ago | 4 / 5 (1) | 0
(Medical Xpress)—Inflammation is an important response in the body - it helps you to kill off invaders such bacteria that could cause a harmful infection. But if it's chronic or uncontrolled, inflammation can also cause ...
Inflammatory disorders May 14, 2013 | not rated yet | 0 |
New research by medical students working in the Breathe Well Centre of Research Excellence at the UTAS School of Medicine has revealed swimming has health benefits for young people with asthma, with no adverse effects on ...
Inflammatory disorders May 10, 2013 | not rated yet | 0
An estimated 4,837,000 asthmatics with allergic bronchopulmonary aspergillosis (ABPA) could benefit substantially from antifungal treatment, say researchers from The University of Manchester and the University of Toronto.
Inflammatory disorders May 08, 2013 | not rated yet | 0
Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...
Inflammatory disorders May 07, 2013 | 4.5 / 5 (2) | 0 |
(HealthDay)—Obese and overweight men and women who suffer from heartburn often report relief when they lose weight, a new study shows.
52 minutes ago | not rated yet | 0 |
(Medical Xpress)—In a recent subgroup analysis of the largest blood pressure treatment trial in history, University of Alabama at Birmingham (UAB) researchers found that women and men react the same to ...
26 minutes ago | not rated yet | 0
Ten years after the Iraq war of 2003 a team of scientists based in Mosul, northern Iraq, have detected high levels of uranium contamination in soil samples at three sites in the province of Nineveh which, coupled with dramatically ...
22 minutes ago | not rated yet | 0
The warning images Brussels proposes to include on tobacco packages in order to reduce consumption do not make the desired impact on smokers because they only find some of them really unpleasant. So, if the ...
12 minutes ago | not rated yet | 0
Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat—its main energy source—and how changes in fat metabolism play ...
2 minutes ago | not rated yet | 0