Bolus calculation, flexible insulin up diabetes control

February 24, 2012
Bolus calculation, flexible insulin up diabetes control

(HealthDay) -- A structured course teaching the benefits of automated bolus calculator (ABC) use and flexible intensive insulin therapy (FIIT) improves metabolic control and satisfaction in patients with type 1 diabetes, according to a study published online Feb. 16 in Diabetes Care.

Signe Schmidt, M.D., of Hvidovre University Hospital in Denmark, and associates evaluated a 16-week randomized clinical trial of 51 patients with to determine the effect of FIIT and ABC use. Eight participants were randomized to a control group; 21 to group teaching, which included FIIT and counting (CarbCount); and 22 to group teaching, which included FIIT and CarbCount using an ABC (CarbCountABC). The received FIIT education without carbohydrate counting.

The researchers found that, at 16 weeks, the within-group change in (HbA1c) was −0.1, −0.8, and −0.7 percent in the control, CarbCount, and CarbCountABC groups, respectively. There was no significant difference between the change in the CarbCount and CarbCountABC groups. The relative change in HbA1c was −0.6 and −0.8 percent in the CarbCount and CarbCountABC groups, respectively, after adjusting for baseline HbA1c (P = 0.082 and 0.017, respectively). In all the study groups there was a significant improvement in treatment satisfaction, with a significantly greater improvement found in the CarbCountABC group.

"The principles of FIIT were successfully communicated to patients in a structured three-hour course," the authors write. "In addition, the study gives indications of increased treatment satisfaction and adherence with the concurrent use of an ABC."

Several authors disclosed financial ties to Roche, which provided glucose meters and bolus calculators. Medtronic provided glucose sensors and iPro2s. The study was partially funded by Novo Nordisk.

Explore further: Low-carb diets prove better at controlling type 2 diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Low-carb diets prove better at controlling type 2 diabetes

January 5, 2009

In a six-month comparison of low-carb diets, one that encourages eating carbohydrates with the lowest-possible rating on the glycemic index leads to greater improvement in blood sugar control, according to Duke University ...

Value of exercise combination shown in diabetes study

December 6, 2010

Performing a combination of aerobic exercise and resistance training has been found to improve glycemic levels among patients 
with type 2 diabetes, compared to patients who did not exercise,
 according to a study ...

Recommended for you

Diets avoiding dry-cooked foods can protect against diabetes

August 24, 2016

Simple changes in how we cook could go a long way towards preventing diabetes, say researchers at the Icahn School of Medicine at Mount Sinai. A new randomized controlled trial, published online July 29 in the journal Diabetologia, ...

New study reveals a novel protein linked to type 2 diabetes

August 16, 2016

Findings from Boston University School of Medicine (BUSM), which appear in eLife, provide a possible explanation as to why most people who are obese develop insulin resistance and type 2 diabetes. A minority of obese individuals, ...

Gene variant explains differences in diabetes drug response

August 9, 2016

The first results from a large international study of patients taking metformin, the world's most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.