Pioneering research will assess the effects of obesity on bone development

February 3, 2012

Researchers from the University of Sheffield are conducting ground-breaking research to determine how body weight and hormones affect bone health from childhood to adulthood.

The innovative study involves using revolutionary bone to look at the internal structure of bones in detail to assess whether body weight and hormones affect during growth.

The research, funded by the National Institute of Health Research (NIHR) Biomedical Research Unit (BRU) for Musculoskeletal Disease will use a state-of-the-art XtremeCT scanner which looks at bones in minute detail, and of which there are only three in the country. The research will take place at the Northern General Hospital and The Children's Hospital Sheffield in partnership with the University.

Dr Paul Dimitri, Consultant Paediatric Endocrinologist and research fellow at the University of Sheffield's Academic Unit of is leading the study.

Dr Dimitri said: "There are concerns that obesity may affect how our bones develop from childhood to adulthood and may lead to an increased risk of fracture or osteoporosis. At the moment, we do not fully understand the impact on the skeleton of being overweight during childhood and adulthood."

Obesity is a major health problem in the United Kingdom and nearly one in four adults and one in five children are now considered obese.

Dr Dimitri added: "If we have a better understanding of the factors that affect we can give better advice to patients, and we may eventually be able to develop new treatments for . In this way, the study may be of benefit to thousands of people in the future."

Explore further: New research shows early bone growth linked to bone density in later life

Related Stories

Recommended for you

An accessible approach to making a mini-brain

October 1, 2015

If you need a working miniature brain—say for drug testing, to test neural tissue transplants, or to experiment with how stem cells work—a new paper describes how to build one with what the Brown University authors say ...

Tension helps heart cells develop normally in the lab

October 1, 2015

The heart is never quite at rest, and it turns out that even in a lab heart cells need a little of that tension. Without something to pull against, heart cells grown from stem cells in a lab dish fail to develop normally.

Dormant viral genes may awaken to cause ALS

September 30, 2015

Scientists at the National Institutes of Health discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS). The ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.