Family history -- a significant way to improve cardiovascular disease risk assessment
A new study by researchers at The University of Nottingham has proved that assessing family medical history is a significant tool in helping GPs spot patients at high risk of heart disease and its widespread use could save lives.
Previous research has suggested that family history can be an indicator of a patient's risk of heart disease but at present family medical details are not systematically collected and used by GPs in cardiovascular risk assessment.
This first-ever clinical investigation into systematically collecting family history as part of cardiovascular disease risk assessment has identified a further five per cent of patients who would benefit from prevention measures. The researchers from the University's Division of Primary Care also found that the gathering of family medical data is simple, low-cost and acceptable to patients.
Leading the study, Professor Nadeem Qureshi said: "Recently there has been great interest in performing genetic tests to identify individuals at high risk of heart disease, but our study has found that simply taking a detailed family history may be as effective, if not more, to identify these individuals. We are thrilled our research has been published in the prestigious international journal, Annals of Internal Medicine which has highlighted the study in its Editorial, agreeing that it is time to take systematic family history collection more seriously."
The large randomised controlled trial was carried out in 24 doctors' practices in the East Midlands and South West England over a six month period. The practices were organised into 12 pairs of one control and one intervention practice each. 748 patients aged 30 to 65 with no previously diagnosed cardiovascular risk were studied.
In all patients the medical staff calculated a standard cardiovascular risk score by inputting core risk factors like age, sex, smoking status, blood pressure and cholesterol into a risk calculator. GPs usually use this score to predict a patient's 10 year risk for cardiovascular disease. In the intervention groups, clinicians also had patients fill in a questionnaire on family history of coronary heart disease. The patient's standard risk was multiplied by 1.5 if a family history of premature heart disease was identified. This is because a patient is more likely to develop Coronary Heart Disease (CHD) if they have a father or brother younger than 55 years who had CHD or a mother or sister younger than 65 with the disease.
Doctors invited patients identified as having a high risk (20 per cent or more) for developing heart disease in the next 10 years for a consultation. The risk was explained and advice offered on lifestyle changes such as diet, exercise and giving up smoking.
The study found that the additional use of systematic family history in cardiovascular risk assessment almost doubles the proportion of individuals identified at high cardiovascular risk.
The research also concludes that the systematic identification of familial risk for CHD offers a potentially low-cost approach to targeting limited resources for screening and prevention interventions in those at high cardiovascular risk. The use of a self-completed tool to do this appears acceptable to patients without causing anxiety, and could lead to more CHD being prevented.
Provided by University of Nottingham
- New tests needed to predict cardiovascular problems in older people more accurately Jan 09, 2009 | not rated yet | 0
- Women less likely than men to change habits that increase heart disease risk Sep 10, 2007 | not rated yet | 0
- Get personal to improve heart health Feb 23, 2009 | not rated yet | 0
- Presence of gum disease may help dentists and physicians identify risk for cardiovascular disease Nov 25, 2008 | not rated yet | 0
- Low risk? Women and young men responsible for large portion of heart attacks Nov 16, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
46 minutes ago Hello :) i'm new to this forum, so excuse me for my straightforwardness ;) I'm working on my bachelor work and i can't find a solution. I'm writing...
siphon and bernouli theorum
2 hours ago 1. I found this diagram on book but there weren't any description.can someone tell me, what its trying to tell specially by those two red lines...
Hot gas expansion rate into outer space
2 hours ago Good Morning Sirs, it seems to be surprisingly hard to get the numbers of a mystery: How fast expand hot rocket exhaust gases into empty space? ...
Magnetic field lines through copper
7 hours ago Hello. Assume an electron gun, as in CRT, made of plumbing copper instead of glass. Using magnetic scanning coils to move electron beam. Will the...
Lagrangian of object with air resistance
9 hours ago So I was going through an ODEs textbook and in a section discussing physical problems, decided that it would be interesting to come up with the...
Does electromagnetic waves are generated by dc current?
9 hours ago I am beginner in physics.I have question that when dc current flow they flow with apparent drift velocity so it appears that it should not emit em...
- More from Physics Forums - Classical Physics
More news stories
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
Cardiology 5 hours ago | not rated yet | 1
Mortality and length of stay are highest in heart failure patients admitted in January, on Friday, and overnight, according to research presented today at the Heart Failure Congress 2013. The analysis of nearly 1 million ...
Cardiology 5 hours ago | not rated yet | 0
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
Cardiology 5 hours ago | 5 / 5 (1) | 4
Transcatheter aortic valve implantation (TAVI) is effective and safe in Asian patients, according to early experience based on first results from a multicentre Asian registry reported at EuroPCR 2013.
Cardiology May 24, 2013 | not rated yet | 0
Routinely measuring fractional flow reserve (FFR) using pressure wire assessment during coronary angiography for diagnosis of chest pain leads to significant changes in the management of one in four patients, according to ...
Cardiology May 24, 2013 | not rated yet | 0
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
5 hours ago | not rated yet | 0
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
22 hours ago | 3 / 5 (2) | 0 |
Talking on a hands-free device while behind the wheel can lead to a sharp increase in errors that could imperil other drivers on the road, according to new research from the University of Alberta.
21 hours ago | not rated yet | 0
(HealthDay)—Comorbid conditions often accompany alopecia areata, according to a study published online May 22 in JAMA Dermatology.
23 hours ago | not rated yet | 0
Kate O'Reilly's spring allergy survival kit includes the usual stuff - nasal sprays, allergy pills and a box of tissues. This season, she's added a new weapon to her line of defense: an app on her smartphone.
22 hours ago | not rated yet | 0