Overeating may double risk of memory loss

February 12, 2012 in Neuroscience

New research suggests that consuming between 2,100 and 6,000 calories per day may double the risk of memory loss, or mild cognitive impairment (MCI), among people age 70 and older. The study was released today and will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. MCI is the stage between normal memory loss that comes with aging and early Alzheimer's disease.

"We observed a dose-response pattern which simply means; the higher the amount of calories consumed each day, the higher the risk of MCI," said study author Yonas E. Geda, MD, MSc, with the Mayo Clinic in Scottsdale, Arizona and a member of the American Academy of Neurology.

The study involved 1,233 people between the ages of 70 and 89 and free of residing in Olmsted County, Minn. Of those, 163 had MCI. Participants reported the amount of calories they ate or drank in a food questionnaire and were divided into three equal groups based on their daily caloric consumption. One-third of the participants consumed between 600 and 1,526 calories per day, one-third between 1,526 and 2,143 and one-third consumed between 2,143 and 6,000 .

The odds of having MCI more than doubled for those in the highest calorie-consuming group compared to those in the lowest calorie-consuming group. The results were the same after adjusting for history of stroke, diabetes, amount of education, and other factors that can affect risk of memory loss. There was no significant difference in risk for the middle group.

"Cutting calories and eating foods that make up a may be a simpler way to prevent as we age," said Geda.

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neurosynchrony
Feb 15, 2012

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While excess calorie consumption is likely a factor in memory encoding and retrieval, could the author's conclusion that overeating may double risk of memory loss be confusing cause and effect? People overeat due to a variety of factors, including chronic stress, history of abuse, grief, etc., which are also implicated in dissociation and memory impairment. If an individual significantly overeats in order to self-regulate, it is likely there is something more to their memory impairment than simply consuming too many calories. Telling someone to eat less and exercise more, like most doctors do, might not fix anything if the problem lies unresolved in the subconscious mind.
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