Cartilage repair gel gives injuries a sporting chance
A cartilage gel being developed by tissue engineers and biochemists at the University of Sydney could bring increased mobility to people living with debilitating sports injuries.
Work has just commenced on an injectable hybrid-hydrogel that mimics chondrocytes, the cells that are found in cartilage.
Chief investigator on the project, Associate Professor Fariba Dehghani, from the Faculty of Engineering and Information Technologies, says the team is targeting these cells because they are responsible for producing and maintaining the structure of cartilage but until now have been extremely hard to repair when damaged.
"Tissue engineering is an emerging science that consists of growing living cells into 3D scaffolds to form whole tissues capable of normal functions," says Professor Dehghani.
"We intend to generate a new family of hybrid biomaterials constructed by precisely blending natural and synthetic components.
"The novel biomaterials that we are developing will establish a foundation for manufactured prefabrication and in situ injections which will promote rapid and targeted healing to the affected region," says Professor Dehghani.
Sports injuries similar to those affecting cricketers or rugby league and soccer players for example could potentially be permanently repaired by the tissue engineering techniques being developed by the team, says Professor Dehghani.
Also working on the project is molecular researcher and co-Chief investigator Professor Tony Weiss from the University's School of Molecular Bioscience, who says:
"When we refine it, this technology has the potential to be used to rebuild other cartilage in many places in the human body, areas that are adversely affected by ageing and disease."
"This is an extremely exciting time for scientists. Our multidisciplinary approach to research gives us the opportunity to blend the best of our skills."
"It promises more rapid advancement of our knowledge and by working together we can accelerate the development of therapies for injuries which in the past many of us have just had to live with," says Professor Weiss.
Provided by University of Sydney
- Progress in tissue engineering to repair joint damage in osteoarthritis Jun 08, 2011 | not rated yet | 0
- Amniotic membrane used to repair human articular cartilage Jun 23, 2010 | not rated yet | 0
- Tissue engineered scaffolding allows reproduction of cartilage tissue May 09, 2007 | not rated yet | 0
- Researchers inject nanofiber spheres carrying cells into wounds to grow tissue Apr 17, 2011 | not rated yet | 0
- Scientists progress in successful tissue engineering Mar 23, 2007 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
How can there be a term called "intestinal metaplasia" of stomach
18 hours ago Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
- More from Physics Forums - Medical Sciences
More news stories
Trends in Helicobacter pylori (H. pylori) and smoking explain a significant proportion of the decline of intestinal-type noncardia gastric adenocarcinoma (NCGA) incidence in US men between 1978 and 2008, and are estimated ...
Medical research 7 hours ago | not rated yet | 0
Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older ...
Medical research 12 hours ago | 5 / 5 (2) | 0 |
Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological ...
Medical research 12 hours ago | 5 / 5 (1) | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
Medical research 13 hours ago | 4.5 / 5 (6) | 0 |
Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat—its main energy source—and how changes in fat metabolism play ...
Medical research 16 hours ago | not rated yet | 0
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
13 hours ago | 4.2 / 5 (5) | 0 |
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
11 hours ago | 4.9 / 5 (9) | 0 |
An experimental sleeping pill from US drug company Merck is effective at helping people fall and stay asleep, according to reviewers at the US Food and Drug Administration, which could soon approve the new drug.
6 hours ago | 3 / 5 (2) | 0
Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...
7 hours ago | 5 / 5 (3) | 0 |
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
8 hours ago | 5 / 5 (1) | 0 |
The gap between life expectancy in patients with a mental illness and the general population has widened since 1985 and efforts to reduce this gap should focus on improving physical health, suggest researchers in a paper ...
6 hours ago | not rated yet | 0