Hops compounds improve health of obese diabetic mice

March 28, 2012

A class of compounds found in hops, the crop generally known for its role in beer production, reduces weight gain in obese and diabetic mice, according to a study published Mar. 28 in the open access journal PLoS ONE.

Eight weeks of treatment with the compounds, called tetrahydro iso-alpha acids, also reduced gut permeability and normalized insulin sensitivity markers in the mice, among other beneficial metabolic effects.

Hops have been known to contain anti-inflammatory compounds with potential medicinal uses for metabolic disorders, like and type 2 diabetes, which are associated with low-grade inflammation. These new results suggest a novel mechanism contributing to the positive effects of the investigated treatment, the authors write. The work was led by Patrice Cani of the Université catholique de Louvain in Brussels, Belgium.

Explore further: The metabolic effects of antipsychotic drugs

More information: Everard A, Geurts L, Van Roye M, Delzenne NM, Cani PD (2012) Tetrahydro iso-Alpha Acids from Hops Improve Glucose Homeostasis and Reduce Body Weight Gain and Metabolic Endotoxemia in High-Fat Diet-Fed Mice. PLoS ONE 7(3): e33858. doi:10.1371/journal.pone.0033858

Related Stories

The metabolic effects of antipsychotic drugs

July 12, 2011

Research to be presented at the upcoming annual meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, may explain why some antipsychotic ...

Recommended for you

Unique molecular atlas of pancreas produced

September 23, 2016

Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between ...

Can long naps cause diabetes?

September 14, 2016

A study presented at a scientific congress Thursday reported a link between long naps and a higher risk of diabetes, though it couldn't say if daytime sleeping was a symptom or a cause.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.