Diabetic polyneuropathy not up with impaired glycemia

March 3, 2012
Diabetic polyneuropathy not up with impaired glycemia

(HealthDay) -- Although significantly increased in subjects with new diabetes, the rates of typical diabetic polyneuropathy (DPN), retinopathy, and nephropathy are not significantly different between subjects with and without impaired glycemia (IG), according to research published in the March issue of Diabetes Care.

Peter J. Dyck, M.D., of the Mayo Clinic in Rochester, Minn., and colleagues conducted a prospective, population-based survey of 150 subjects without IG, 174 with IG, and 218 with new diabetes to determine whether DPN, retinopathy, or nephropathy are more prevalent in subjects with IG than in healthy subjects.

The researchers found that the frequency of retinopathy and nephropathy was not significantly different between patients with and without IG, but was greater in those with new diabetes. The frequency of narrowly defined DPN was 2, 1.7, and 7.8 percent in non-IG, IG, and new diabetes subjects, respectively. Using a broader definition, the frequency of DPN was 12.7, 12.6, and 17.4 percent in non-IG, IG, and new diabetes subjects, respectively.

"Prevalence of typical DPN, , and nephropathy was significantly increased only in subjects with new diabetes," the authors write. "For atypical DPN, such an increase was not observed even in subjects with new diabetes. In , explanations other than IG should be sought for patients with atypical DPN (chronic idiopathic axonal polyneuropathy) who have IG."

Explore further: Prediabetes may not explain diabetic polyneuropathies

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Prediabetes may not explain diabetic polyneuropathies

February 22, 2012

In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations ...

Recommended for you

Major fall in diabetes-related amputations since the 1990s

November 22, 2015

A major new study has found a significant reduction in diabetes-related amputations since the mid-1990s, credited to improvements in diabetes care over this period. The research is published in Diabetologia (the journal of ...

Blocking immune cell treats new type of age-related diabetes

November 18, 2015

Diabetes is often the result of obesity and poor diet choices, but for some older adults the disease might simply be a consequence of aging. New research has discovered that diabetes—or insulin resistance—in aged, lean ...

Bacteria may cause type 2 diabetes

June 1, 2015

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers ...

Engineered hot fat implants reduce weight gain in mice

August 20, 2015

Scientists at the University of California, Berkeley, have developed a novel way to engineer the growth and expansion of energy-burning "good" fat, and then found that this fat helped reduce weight gain and lower blood glucose ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.