Albendazole cuts enteric parasite prevalence in refugees

Albendazole cuts enteric parasite prevalence in refugees

(HealthDay) -- The administration of a single 600-mg dose of albendazole to United States-bound refugees prior to departure from Africa and Southeast Asia reduces the prevalence of intestinal nematodes, according to a study published in the April 19 issue of the New England Journal of Medicine.

Stephen J. Swanson, M.D., of the Epidemic Intelligence Service in Atlanta, and colleagues conducted a of 26,956 refugees from Africa and Southeast Asia. The refugees underwent stool specimen screening for intestinal parasites. The prevalence of intestinal nematodes, schistosoma species, giardia, and entamoeba was compared among refugees who migrated before and after the U.S. Centers for Disease Control and Prevention's recommendation of presumptive predeparture albendazole treatment.

A total of 22,586 refugees received albendazole and 4,370 did not. The researchers found that 20.8 percent of untreated refugees versus 4.7 percent of treated refugees carried one or more stool nematodes. The most common parasite in untreated refugees was , and in treated refugees was trichuris. In an age-, sex-, and region-adjusted analysis, compared with untreated refugees, albendazole-treated refugees were significantly less likely to have any nematodes, ascaris, hookworm, or trichuris, but were no less likely to have giardia or entamoeba. No albendazole-related were reported.

"These data provide evidence that implementation of an overseas protocol for presumptive single-dose albendazole therapy in refugees was associated with substantial decreases in infections with multiple intestinal parasites," the authors write. "Targeting these diseases among refugees has yielded reductions in parasite burdens and may improve the health of this population."

More information: Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Schooling protects fleeing children from disease

Feb 03, 2012

Refugee children have scant access to medical care and are particularly vulnerable to disease. Fresh research results from the University of Copenhagen show that just a few hours of schooling a week may have a pronounced ...

Recommended for you

Chile's Bachelet sends abortion bill to Congress

2 hours ago

Chile's President Michelle Bachelet on Saturday pressed ahead with plans to decriminalize abortion in certain cases, a decades-old taboo in one of Latin America's most socially conservative countries.

Jamaica Senate starts debate on pot decriminalization bill

Jan 30, 2015

Jamaica's Senate on Friday started debating a bill that would decriminalize possession of small amounts of pot and establish a licensing agency to regulate a lawful medical marijuana industry on the island where the drug ...

Can Lean Management improve hospitals?

Jan 30, 2015

Waiting times in hospital emergency departments could be cut with the introduction of Lean Management and Six Sigma techniques according to new research.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.