Smoking found to be a risk factor for Barrett's esophagus

Smoking found to be a risk factor for barrett's esophagus
Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.

(HealthDay) -- Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.

To investigate the association between cigarette smoking and Barrett's esophagus, Michael B. Cook, Ph.D., of the in Bethesda, Md., and associates analyzed data from five case-control studies within the international Barrett's and Consortium. Data were compared for 1,059 patients with Barrett's esophagus, 1,332 controls with (GERD), and 1,143 population-based controls.

The researchers found that patients with Barrett's esophagus were significantly more likely to have ever smoked cigarettes than the population-based control group or the GERD cohort (odds ratio, 1.67 and 1.61, respectively). There was an increased risk of Barrett's esophagus with increasing pack-years of smoking. Among individuals who ever smoked and had heartburn or regurgitation, the attributable proportion of disease was estimated at 0.39.

"Cigarette smoking is a risk factor for Barrett's esophagus," the authors conclude. "The evidence we present for a biological interaction between smoking and heartburn/regurgitation suggest that cigarette smoking has multifaceted effects in the development of this precancerous metaplasia."

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Is Australia prepared for Ebola?

2 hours ago

Australia needs to be proactive about potential disease outbreaks like Ebola and establish a national centre for disease control.

Dallas hospital confirms first Ebola case in US

7 hours ago

A patient at a Dallas hospital has tested positive for Ebola, the first case of the disease to be diagnosed in the United States, federal health officials announced Tuesday.

First case of Ebola diagnosed in US

9 hours ago

The United States has diagnosed its first case of the deadly Ebola virus in a man who became infected in Liberia and traveled to Texas, US health officials said Tuesday.

Study finds acupuncture does not improve chronic knee pain

10 hours ago

Among patients older than 50 years with moderate to severe chronic knee pain, neither laser nor needle acupuncture provided greater benefit on pain or function compared to sham laser acupuncture, according to a study in the ...

User comments