Smoking found to be a risk factor for Barrett's esophagus
April 11, 2012 in Diseases, Conditions, Syndromes
Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.
(HealthDay) -- Cigarette smoking may be a modifiable risk factor for Barrett's esophagus, according to a study published in the April issue of Gastroenterology.
To investigate the association between cigarette smoking and Barrett's esophagus, Michael B. Cook, Ph.D., of the National Cancer Institute in Bethesda, Md., and associates analyzed data from five case-control studies within the international Barrett's and Esophageal Adenocarcinoma Consortium. Data were compared for 1,059 patients with Barrett's esophagus, 1,332 controls with gastroesophageal reflux disease (GERD), and 1,143 population-based controls.
The researchers found that patients with Barrett's esophagus were significantly more likely to have ever smoked cigarettes than the population-based control group or the GERD cohort (odds ratio, 1.67 and 1.61, respectively). There was an increased risk of Barrett's esophagus with increasing pack-years of smoking. Among individuals who ever smoked and had heartburn or regurgitation, the attributable proportion of disease was estimated at 0.39.
"Cigarette smoking is a risk factor for Barrett's esophagus," the authors conclude. "The evidence we present for a biological interaction between smoking and heartburn/regurgitation suggest that cigarette smoking has multifaceted effects in the development of this precancerous metaplasia."
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2012 HealthDay. All rights reserved.
-
Risk of esophageal cancer in patients with Barrett’s esophagus
Oct 14, 2011 |
not rated yet |
0
-
Esophageal cancer risk higher in medically treated GERD patients with fewest symptoms
Jul 18, 2011 |
not rated yet |
0
-
Treatment of Barrett's esophagus may lower risk of esophageal cancer
Apr 04, 2011 |
not rated yet |
0
-
Drinking wine lowers risk of Barrett's esophagus, precursor to esophageal cancer
Mar 02, 2009 |
not rated yet |
0
-
Barrett's esophagus patients have same survival rates as general population
Oct 26, 2009 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011
- More from Physics Forums - Independent Research
More news stories
FDA warns of infections tied to Tennessee pharmacy
(AP)—Government health officials are investigating several health problems reported with potentially contaminated medications made by a Tennessee specialty pharmacy.
Diseases, Conditions, Syndromes
18 hours ago |
not rated yet |
0
Comorbidities common with alopecia areata
(HealthDay)—Comorbid conditions often accompany alopecia areata, according to a study published online May 22 in JAMA Dermatology.
Diseases, Conditions, Syndromes
19 hours ago |
not rated yet |
0
Top-ranked golfer beats scoliosis
(HealthDay)—As a world-class golfer, Stacy Lewis' accomplishments are remarkable. But it was a physical challenge in her childhood that defined her ascent to the top of her sport.
Diseases, Conditions, Syndromes
20 hours ago |
not rated yet |
0
Saudi to send animal samples to US in coronavirus probe (Update)
Saudi Arabia said Friday it would send samples taken from animals possibly infected with a deadly SARS-like virus to the United States for testing in a bid to find the source of disease.
Diseases, Conditions, Syndromes
23 hours ago |
not rated yet |
0
WHO voices deep concern over spread of SARS-like virus
The World Health Organization voiced deep concern Thursday over the SARS-like virus that has killed 22 people in less than a year, saying it might potentially spread more widely between humans.
Diseases, Conditions, Syndromes
May 24, 2013 |
5 / 5 (1) |
0
First drug to improve heart failure mortality in over a decade
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality ...
Heart failure accelerates male 'menopause'
Heart failure accelerates the aging process and brings on early andropausal syndrome (AS), according to research presented today at the Heart Failure Congress 2013. AS, also referred to as male 'menopause', was four times ...
Hormone levels may provide key to understanding psychological disorders in women
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
Feds fight morning-after pill age ruling in NY
(AP)—Department of Justice lawyers have again asked a federal appeals court in New York to delay lifting age restrictions and prescription requirements on an emergency contraceptive popularly known as the morning-after ...
Death highest in heart failure patients admitted in January, on Friday, and overnight
Mortality and length of stay are highest in heart failure patients admitted in January, on Friday, and overnight, according to research presented today at the Heart Failure Congress 2013. The analysis of nearly 1 million ...
Researchers identify first drug targets in childhood genetic tumor disorder
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
