New fat grafting procedures improve breast reconstruction

New fat grafting procedures improve breast reconstruction
Two autologous fat grafting procedures, enhanced stromal vascular fraction and platelet-rich plasma fat grafting, maintain breast volume and three-dimensional contour better than the standard fat grafting procedure, according to a study published online April 13 in Stem Cells Translational Medicine.

(HealthDay) -- Two autologous fat grafting procedures, enhanced stromal vascular fraction (SVF) and platelet-rich plasma (PRP) fat grafting, maintain breast volume and three-dimensional contour better than the standard fat grafting procedure, according to a study published online April 13 in Stem Cells Translational Medicine.

Pietro Gentile, M.D., of the University of Rome Tor Vergata, and colleagues conducted a comparative translational study involving 23 women affected by soft tissue defects to compare the effects of two autologous fat grafting procedures in maintaining fat volume after breast reconstruction surgery. SVF-enhanced autologous fat grafting (performed in 10 women) and fat grafting with PRP (performed in 13 ) were compared with the results achieved in a control group (10 patients) who were treated with a standard centrifuged fat grafting procedure.

The researchers found that, after one year, 63 and 69 percent maintenance of contour restoring and three-dimensional volume was seen in the SVF and PRP groups, respectively, compared with 39 percent in the control group.

"We conclude that engineered fat grafting based on the [addition] of SVF or PRP is a reliable alternative to breast implant based on some initial indications," the authors write. "Additional study is necessary to evaluate the efficacy of this method further."

More information: Stem Cells Trans Med, April 2012 sctm.2011-0065. doi: 10.5966/sctm.2011-0065

Related Stories

The role of fat in assessing breast cancer risk

Oct 26, 2011

It is known that a high proportion of dense breast tissue, as seen with a mammogram, is associated with a high risk of breast cancer. But the role of non-dense fat tissue in the breast is less clear. New research published ...

Fat cells become useful stem cells in tissue reconstruction

Dec 23, 2010

Two studies appearing in the current issue of Cell Transplantation 19(10) discuss stem cells derived from adipose (fat) cells and their potential use in plastic surgery and tissue reconstruction. The studies are now free ...

Recommended for you

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.