Heart surgery safe for compensated cirrhosis patients

April 27, 2012
Heart surgery safe for compensated cirrhosis patients

(HealthDay) -- Patients with compensated cirrhosis, defined by a Child-Pugh (CP) score of <8, have no significant increase in postoperative mortality and morbidity following cardiac surgery with cardiopulmonary bypass, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

To investigate the effect of on mortality and morbidity after cardiac surgery, Carole Macaron, M.D., of the Cleveland Clinic, and colleagues conducted a of 54 patients with cirrhosis and 216 matched controls without cirrhosis. All participants underwent cardiac surgery with cardiopulmonary bypass at the same institution between 1992 and 2009. For patients with cirrhosis, the CP class and score were calculated.

The researchers found that, within 90 days of surgery, the mortality rate was 4.6 percent for those with a CP score <8, similar to that observed in control patients without cirrhosis, and significantly lower than the mortality rate for patients with a CP score of ≥8 (70 percent). Hospital stays were significantly shorter for patients with CP scores <8, (15.6 days, versus 26 days for those with CP scores ≥8). Renal failure and the need for dialysis were significantly less likely in those with CP scores <8. These values were similar to those of matched controls.

"Among the patients with liver cirrhosis, patients with CP score <8 might safely undergo with cardiopulmonary bypass," the authors write. "Our study shows that such patients had similar outcomes in terms of mortality and morbidity compared with their matched controls."

Explore further: Study suggests obesity accelerates progression of cirrhosis

More information: Abstract
Full Text (subscription or payment may be required)
Editorial

Related Stories

Study suggests obesity accelerates progression of cirrhosis

July 21, 2011

Researchers from the United States and Europe involved in an NIH-funded multicenter study have determined that increased body mass index (BMI) is an independent predictor of clinical decompensation in patients with compensated ...

The economic cost of advanced liver disease

November 7, 2011

Health care costs for hepatitis C patients with end-stage liver disease are nearly 2.5 times higher than those in the early stages, according to a Henry Ford Hospital study.

Recommended for you

Gut environment could reduce severity of malaria

February 8, 2016

Microorganisms in the gut could play a role in reducing the severity of malaria, according to a new study co-authored by researchers at the University of Tennessee, Knoxville, and the University of Louisville.

Easier diagnosis for fungal infection of the lungs

January 18, 2016

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.