Study: No link between depression, nasal obstruction
While mood disorders like depression or anxiety tend to negatively affect treatment for allergies and chronic rhinosinusitis, the same cannot be said for patients with nasal obstructions such as deviated septum, according to researchers at Henry Ford Hospital.
The new study shows mood disorders are not linked to either nasal obstructive symptoms or the failure of nasal obstruction surgery.
Results also suggest that those patients with nasal obstruction caused by septal deviation a blockage of the nasal airway caused by a portion of cartilage or bony septum who do not have signs and symptoms of allergic rhinitis would not benefit from depression screening if nasal treatment is unsuccessful.
"Although the literature supports more negative outcomes of allergic rhinitis and chronic rhinosinusitis patients with mood disorders, our data does not show a similar relationship for septal deviation," says study author Lamont R. Jones, M.D., vice chair, Department of Otolaryngology-Head and Neck Surgery at Henry Ford.
"It's unclear why depression would exacerbate symptoms after certain nasal procedures, but not others; although it's very likely that the difference could be due to the inflammatory nature of rhinosinusitis and seasonal allergies."
The study will be presented this week at the Combined Otolaryngological Spring Meetings in San Diego.
Nasal obstruction is a common complaint among patients in otolaryngology (ear, nose and throat) clinics. It is often caused by inflammation from inhalant allergies, mucosal edema from chronic rhinosinusitis, and mechanical obstruction from a deflected septum.
Treatment ranges from nasal saline irrigations, topical corticosteroid sprays, allergy control and surgery. Yet some patients lack long-lasting benefit from treatment. According to some research reports, many of these difficult-to-treat nasal patients may also have a mood disorder.
While the effect of depression on chronic rhinosinusitis has been widely reported with patients requiring longer follow-up and having less satisfaction with nasal and sinus surgery outcome little is known about the effect of mood disorders on nasal obstruction symptoms and surgical outcomes.
To determine if there might be a possible link between surgical failure of non-allergic nasal obstruction and a co-morbid mood disorder, Dr. Jones and Brandon Musgrave, M.D., conducted a retrospective review of 437 patients who had surgery between 2005 and 2010 for septal deviation at Henry Ford.
Among the patients, 398 (91 percent) had a successful surgical outcome for nasal obstruction, while 39 (nearly 9 percent) did not.
Within the surgical success group, 31 percent had a co-morbid mood disorder, compared to 36 percent of the surgical failures. The researchers note, however, that this difference in mood disorder prevalence was not statistically significant.
According to study findings, the only significant result was that successfully treated nasal obstruction patients had shorter post-operative follow up.
That finding, notes Dr. Jones, is to be expected as patients with persistent nasal symptoms are more likely to continue following up with their surgeon for potential relief.
Provided by Henry Ford Health System
- Study finds technique for nasal obstruction helps patients breathe easier May 19, 2008 | not rated yet | 0
- Long-term bouts with hay fever worsen ability to breathe through your nose Jun 01, 2008 | not rated yet | 0
- Sinus problems are treated well with safe, inexpensive treatment Nov 19, 2007 | not rated yet | 0
- Patients seek revision plastic surgery to correct asymmetric nasal tips, breathing obstructions Sep 20, 2010 | not rated yet | 0
- Imaging tests identify role of allergies in chronic sinus disease Dec 21, 2009 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
No new human cases of the H7N9 virus have been recorded in China for a week, national health authorities said, for the first time since the outbreak began in March.
Diseases, Conditions, Syndromes 33 minutes ago | not rated yet | 0
A Nobel prize-winning scientist Tuesday played down "shock-horror scenarios" that a new virus strain will emerge with the potential to kill millions of people.
Diseases, Conditions, Syndromes 51 minutes ago | 5 / 5 (1) | 0
Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio, the online open-access journal of the American Society for Microb ...
Diseases, Conditions, Syndromes 5 hours ago | 5 / 5 (1) | 0
(AP)—Federal investigators probing the hantavirus outbreak blamed for three deaths at Yosemite National Park recommend that design changes to tent cabins and other lodging run by private concessionaires first be reviewed ...
Diseases, Conditions, Syndromes 11 hours ago | not rated yet | 0
A new diagnostic test for a worm infection that can lead to severe enlargement and deformities of the legs and genitals is far more sensitive than the currently used test, according to results of a field ...
Diseases, Conditions, Syndromes 12 hours ago | not rated yet | 0 |
(Medical Xpress)—A three-year multinational study has tracked and detailed the progression of Huntington's disease (HD), predicting clinical decline in people carrying the HD gene more than 10 years before ...
44 seconds ago | not rated yet | 0
Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression.
1 hour ago | not rated yet | 0 |
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
11 hours ago | 4.6 / 5 (13) | 5 |
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
14 hours ago | 4.8 / 5 (12) | 2 |
Children who have suffered maltreatment are 36% more likely to be obese in adulthood compared to non-maltreated children, according to a new study by King's College London. The authors estimate that the prevention or effective ...
1 hour ago | not rated yet | 0
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
14 hours ago | 4.8 / 5 (6) | 2 |