Meds, clinic noncompliance linked to mortality in diabetes

April 24, 2012
Meds, clinic noncompliance linked to mortality in diabetes

(HealthDay) -- Insulin-treated patients with type 2 diabetes who are noncompliant with their medication or clinic appointments face increased all-cause mortality, according to a study published online April 17 in Diabetes Care.

Craig J. Currie, Ph.D., of Cardiff University in the United Kingdom, and colleagues extracted data from the medical records of 15,984 patients with type 2 diabetes who were treated with insulin and had received a prescription for an oral antidiabetic agent. Records were assessed for medication noncompliance (not taking medications as prescribed) or medical appointment nonattendance (missing more than one scheduled visit).

The researchers found that clinic nonattenders were more likely to be smokers, younger, have higher glycated hemoglobin, and have more prior primary care contacts and significantly greater morbidity. Medication noncompliers were more likely to have higher glycated hemoglobin and more prior primary care contacts; they were also significantly more likely to be women, smokers, and have greater morbidity. After adjusting for confounding variables, medication noncompliance, missing one or two clinic appointments, and missing more than two appointments were independent risk factors for all-cause mortality (hazard ratios, 1.579, 1.163, and 1.605, respectively).

"Medication noncompliance and clinic nonattendance, assessed during routine care by or their staff, were independently associated with increased all-cause mortality in patients with type 2 diabetes receiving insulin," the authors write.

Several authors disclosed to medical device and pharmaceutical companies, including , which funded this study.

Explore further: More frequent office visits associated with improvements in risk factors for patients with diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Combo of diabetes, depression increases post-MI mortality

February 27, 2012

(HealthDay) -- Having both diabetes and depression significantly increases the risk of dying in the years following a heart attack, beyond the increased risk from either condition alone, according to a study published in ...

Recommended for you

Unique molecular atlas of pancreas produced

September 23, 2016

Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between ...

Can long naps cause diabetes?

September 14, 2016

A study presented at a scientific congress Thursday reported a link between long naps and a higher risk of diabetes, though it couldn't say if daytime sleeping was a symptom or a cause.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.